Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer

由 Whitton, Bradleigh, Okamoto, Haruko, Packham, Graham, Crabb, Simon J.
發表在 Cancer Med (2018)

V-ATPase inhibition decreases mutant androgen receptor activity in castrate-resistant prostate cancer

由 Whitton, Bradleigh, Okamoto, Haruko, Rose-Zerilli, Matthew, Packham, Graham, Crabb, Simon J.
發表在 Mol Cancer Ther (2021)

Epigenetic modulators as therapeutic targets in prostate cancer

由 Graça, Inês, Pereira-Silva, Eva, Henrique, Rui, Packham, Graham, Crabb, Simon J., Jerónimo, Carmen
發表在 Clin Epigenetics (2016)

Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue...

由 Crabb, Simon J, Bajdik, Chris D, Leung, Samuel, Speers, Caroline H, Kennecke, Hagen, Huntsman, David G, Gelmon, Karen A
出版 2008

Thioflavin S (NSC71948) Interferes with Bcl-2-Associated Athanogene (BAG-1)-Mediated Protein-Protein Interactions

由 Sharp, Adam, Crabb, Simon J., Johnson, Peter W. M., Hague, Angela, Cutress, Ramsey, Townsend, Paul A., Ganesan, A., Packham, Graham
出版 2009

ProCAID: a phase I clinical trial to combine the AKT inhibitor AZD5363 with docetaxel and prednisolone chemotherapy for metastatic castration resistant prostate cancer

由 Crabb, Simon J., Birtle, Alison J., Martin, Karen, Downs, Nichola, Ratcliffe, Ian, Maishman, Tom, Ellis, Mary, Griffiths, Gareth, Thompson, Stuart, Ksiazek, Lidia, Khoo, Vincent, Jones, Robert J.
發表在 Invest New Drugs (2017)

The Prognostic Role of the Change in Neutrophil-to-Lymphocyte Ratio During Neoadjuvant Chemotherapy in Patients with Muscle-Invasive Bladder Cancer: A Retrospective, Multi-Institut...

由 Kaiser, Jeenan, Li, Haocheng, North, Scott A., Leibowitz-Amit, Raya, Seah, Jo-An, Morshed, Nisha, Chau, Caroline, Lee-Ying, Richard, Heng, Daniel Y.C., Sridhar, Srikala, Crabb, Simon J., Alimohamed, Nimira S.
發表在 Bladder Cancer (2018)

LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models

由 Regufe da Mota, Sergio, Bailey, Sarah, Strivens, Rosemary A., Hayden, Annette L., Douglas, Leon R., Duriez, Patrick J., Borrello, M. Teresa, Benelkebir, Hanae, Ganesan, A., Packham, Graham, Crabb, Simon J.
發表在 Cancer Cell Int (2018)

Persistent Neutrophil to Lymphocyte Ratio >3 during Treatment with Enzalutamide and Clinical Outcome in Patients with Castration-Resistant Prostate Cancer

由 Conteduca, Vincenza, Crabb, Simon J., Jones, Robert J., Caffo, Orazio, Elliott, Tony, Scarpi, Emanuela, Fabbri, Paolo, Derosa, Lisa, Massari, Francesco, Numico, Gianmauro, Zarif, Sunnya, Hanna, Catherine, Maines, Francesca, Joyce, Helen, Lolli, Cristian, De Giorgi, Ugo
發表在 PLoS One (2016)

Systemic immune-inflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib

由 Lolli, Cristian, Basso, Umberto, Derosa, Lisa, Scarpi, Emanuela, Sava, Teodoro, Santoni, Matteo, Crabb, Simon J., Massari, Francesco, Aieta, Michele, Conteduca, Vincenza, Maruzzo, Marco, La Russa, Francesca, Wheater, Matthew, Berardi, Rossana, Galli, Luca, De Giorgi, Ugo
發表在 Oncotarget (2016)

Phase I trial of DNA methyltransferase inhibitor guadecitabine combined with cisplatin and gemcitabine for solid malignancies including urothelial carcinoma (SPIRE)

由 Crabb, Simon J., Danson, Sarah, Catto, James W.F., Hussain, Syed, Chan, Danna, Dunkley, Denise, Downs, Nichola, Marwood, Ellice, Day, Laura, Saunders, Geoff, Light, Michelle, Whitehead, Amy, Ellis, Deborah, Sarwar, Naveed, Enting, Deborah, Birtle, Alison, Johnson, Bernadette, Huddart, Robert, Griffiths, Gareth
發表在 Clin Cancer Res (2021)

Body Mass Index in Patients Treated with Cabozantinib for Advanced Renal Cell Carcinoma: A New Prognostic Factor?

由 Santoni, Matteo, Massari, Francesco, Bracarda, Sergio, Procopio, Giuseppe, Milella, Michele, De Giorgi, Ugo, Basso, Umberto, Aurilio, Gaetano, Incorvaia, Lorena, Martignetti, Angelo, Rizzo, Mimma, Cartenì, Giacomo, Grande, Enrique, Matrana, Marc R., Crabb, Simon J., Vau, Nuno, Sorgentoni, Giulia, Cimadamore, Alessia, Montironi, Rodolfo, Battelli, Nicola
發表在 Diagnostics (Basel) (2021)

Venous Thromboembolism Risk in Patients With Locoregional Urothelial Tract Tumors

由 Ramos, Jorge D., Wingate, Jonathan T., Gulati, Roman, Plimack, Elizabeth R., Harshman, Lauren C., Powles, Thomas, Crabb, Simon J., Niegisch, Guenter, Bellmunt, Joaquim, Ladoire, Sylvain, De Giorgi, Ugo, Hussain, Syed, Alva, Ajjai S., Baniel, Jack, Agarwal, Neeraj, Rosenberg, Jonathan E., Vaishampayan, Ulka N., Galsky, Matthew D., Yu, Evan Y.
發表在 Clin Genitourin Cancer (2017)

Tumor Downstaging as an Intermediate Endpoint to Assess the Activity of Neoadjuvant Systemic Therapy in Patients With Muscle-Invasive Bladder Cancer

由 Martini, Alberto, Jia, Rachel, Ferket, Bart S., Waingankar, Nikhil, Plimack, Elizabeth R., Crabb, Simon J., Harshman, Lauren C., Yu, Evan Y., Powles, Thomas, Rosenberg, Jonathan E., Pal, Sumanta K., Vaishampayan, Ulka N., Necchi, Andrea, Wiklund, N. Peter, Mehrazin, Reza, Mazumdar, Madhu, Sfakianos, John P., Galsky, Matthew D.
發表在 Cancer (2019)

Venous thromboembolism in metastatic urothelial carcinoma or variant histologies: incidence, associative factors, and effect on survival

由 Ramos, Jorge D., Casey, Martin F., Crabb, Simon J., Bamias, Aristotelis, Harshman, Lauren C., Wong, Yu‐Ning, Bellmunt, Joaquim, De Giorgi, Ugo, Ladoire, Sylvain, Powles, Thomas, Pal, Sumanta K., Niegisch, Guenter, Recine, Federica, Alva, Ajjai, Agarwal, Neeraj, Necchi, Andrea, Vaishampayan, Ulka N., Rosenberg, Jonathan E., Galsky, Matthew D., Yu, Evan Y.
發表在 Cancer Med (2016)

COAST (Cisplatin ototoxicity attenuated by aspirin trial): A phase II double-blind, randomised controlled trial to establish if aspirin reduces cisplatin induced hearing-loss

由 Crabb, Simon J., Martin, Karen, Abab, Julia, Ratcliffe, Ian, Thornton, Roger, Lineton, Ben, Ellis, Mary, Moody, Ronald, Stanton, Louise, Galanopoulou, Angeliki, Maishman, Tom, Geldart, Thomas, Bayne, Mike, Davies, Joe, Lamb, Carolynn, Popat, Sanjay, Joffe, Johnathan K., Nutting, Chris, Chester, John, Hartley, Andrew, Thomas, Gareth, Ottensmeier, Christian, Huddart, Robert, King, Emma
發表在 Eur J Cancer (2017)

Neoadjuvant vs. Adjuvant Chemotherapy in Muscle Invasive Bladder Cancer (MIBC): Analysis From the RISC Database

由 Del Bene, Gabriella, Calabrò, Fabio, Giannarelli, Diana, Plimack, Elizabeth R., Harshman, Lauren C., Yu, Evan Y., Crabb, Simon J., Pal, Sumanta Kumar, Alva, Ajjai S., Powles, Thomas, De Giorgi, Ugo, Agarwal, Neeraj, Bamias, Aristotelis, Ladoire, Sylvain, Necchi, Andrea, Vaishampayan, Ulka N., Niegisch, Günter, Bellmunt, Joaquim, Baniel, Jack, Galsky, Matthew D., Sternberg, Cora N.
發表在 Front Oncol (2018)

Pan-AKT Inhibitor Capivasertib With Docetaxel and Prednisolone in Metastatic Castration-Resistant Prostate Cancer: A Randomized, Placebo-Controlled Phase II Trial (ProCAID)

由 Crabb, Simon J., Griffiths, Gareth, Marwood, Ellice, Dunkley, Denise, Downs, Nichola, Martin, Karen, Light, Michelle, Northey, Josh, Wilding, Sam, Whitehead, Amy, Shaw, Emily, Birtle, Alison J., Bahl, Amit, Elliott, Tony, Westbury, Charlotte, Sundar, Santhanam, Robinson, Angus, Jagdev, Satinder, Kumar, Satish, Rooney, Claire, Salinas-Souza, Carolina, Stephens, Christine, Khoo, Vincent, Jones, Robert J.
發表在 J Clin Oncol (2021)

Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis

由 de Jong, Joep J., Liu, Yang, Robertson, A. Gordon, Seiler, Roland, Groeneveld, Clarice S., van der Heijden, Michiel S., Wright, Jonathan L., Douglas, James, Dall’Era, Marc, Crabb, Simon J., van Rhijn, Bas W. G., van Kessel, Kim E. M., Davicioni, Elai, Castro, Mauro A. A., Lotan, Yair, Zwarthoff, Ellen C., Black, Peter C., Boormans, Joost L., Gibb, Ewan A.
發表在 Genome Med (2019)

Real-World Data on Cabozantinib in Previously Treated Patients with Metastatic Renal Cell Carcinoma: Focus on Sequences and Prognostic Factors

由 Santoni, Matteo, Heng, Daniel Y., Bracarda, Sergio, Procopio, Giuseppe, Milella, Michele, Porta, Camillo, Matrana, Marc R., Cartenì, Giacomo, Crabb, Simon J., De Giorgi, Ugo, Basso, Umberto, Masini, Cristina, Calabrò, Fabio, Vitale, Maria Giuseppa, Santini, Daniele, Massari, Francesco, Galli, Luca, Fornarini, Giuseppe, Ricotta, Riccardo, Buti, Sebastiano, Zucali, Paolo, Caffo, Orazio, Morelli, Franco, Carrozza, Francesco, Martignetti, Angelo, Gelibter, Alain, Iacovelli, Roberto, Mosca, Alessandra, Atzori, Francesco, Vau, Nuno, Incorvaia, Lorena, Ortega, Cinzia, Scarpelli, Marina, Lopez-Beltran, Antonio, Cheng, Liang, Paolucci, Vittorio, Graham, Jeffrey, Pierce, Erin, Scagliarini, Sarah, Sepe, Pierangela, Verzoni, Elena, Merler, Sara, Rizzo, Mimma, Sorgentoni, Giulia, Conti, Alessandro, Piva, Francesco, Cimadamore, Alessia, Montironi, Rodolfo, Battelli, Nicola
發表在 Cancers (Basel) (2019)