Epigenome manipulation as a pathway to new natural product scaffolds and their congeners

door Cichewicz, Robert H.
Gepubliceerd in 2009

Chlorinated Polyketide Obtained from a Daldinia sp. Treated with the Epigenetic Modifier Suberoylanilide Hydroxamic Acid

door Du, Lin, King, Jarrod B., Cichewicz, Robert H.
Gepubliceerd in J Nat Prod (2014)

Chemoreactive Natural Products Afford Resistance against Disparate Antibiotics and Toxins()

door Du, Lin, You, Jianlan, Nicholas, Kenneth M., Cichewicz, Robert H.
Gepubliceerd in Angew Chem Int Ed Engl (2016)

Production of Cytotoxic Glidobactins/Luminmycins by Photorhabdus asymbiotica in Liquid Media and Live Crickets

door Theodore, Christine M., King, Jarrod B., You, Jianlan, Cichewicz, Robert H.
Gepubliceerd in 2012

Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer

door Robles, Andrew J., Cai, Shengxin, Cichewicz, Robert H., Mooberry, Susan L.
Gepubliceerd in Breast Cancer Res Treat (2016)

Maximiscin Induces DNA damage, Activates DNA Damage Response Pathways and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer

door Robles, Andrew J., Du, Lin, Cichewicz, Robert H., Mooberry, Susan L.
Gepubliceerd in J Nat Prod (2016)

Probing the metabolic aberrations underlying mutant huntingtin toxicity in yeast and assessing their degree of preservation in humans and mice

door Joyner, P. Matthew, Matheke, Ronni M., Smith, Lindsey M., Cichewicz, Robert H.
Gepubliceerd in 2010

Reappraising the structures and distribution of metabolites from black aspergilli containing uncommon 2-benzyl-4H-pyran-4-one and 2-benzylpyridin-4(1H)-one systems

door Henrikson, Jon C., Ellis, Trevor K., King, Jarrod B., Cichewicz, Robert H.
Gepubliceerd in 2011

Waikialoid A Suppresses Hyphal Morphogenesis and Inhibits Biofilm Development in Pathogenic Candida albicans

door Wang, Xiaoru, You, Jianlan, King, Jarrod B., Powell, Douglas R., Cichewicz, Robert H.
Gepubliceerd in 2012

Small-molecule suppressors of Candida albicans biofilm formation synergistically enhance the antifungal activity of amphotericin B against clinical Candida isolates

door You, Jianlan, Du, Lin, King, Jarrod B., Hall, Brian E., Cichewicz, Robert H.
Gepubliceerd in 2013

Bioactive Sulfur-Containing Sulochrin Dimers and Other Metabolites from an Alternaria sp. Isolate from a Hawaiian Soil Sample

door Cai, Shengxin, King, Jarrod B., Du, Lin, Powell, Douglas R., Cichewicz, Robert H.
Gepubliceerd in 2014

Mutanobactin A from the human oral pathogen Streptococcus mutans is a cross-kingdom regulator of the yeast-mycelium transition

door Joyner, P. Matthew, Liu, Jinman, Zhang, Zhijun, Merritt, Justin, Qi, Fengxia, Cichewicz, Robert H.
Gepubliceerd in 2010

Cytotoxic Dimeric Epipolythiodiketopiperazines from the Ascomycetous Fungus Preussia typharum

door Du, Lin, Robles, Andrew J., King, Jarrod B., Mooberry, Susan L., Cichewicz, Robert H.
Gepubliceerd in 2014

A Potent HDAC Inhibitor, 1-Alaninechlamydocin, from a Tolypocladium sp. Induces G2/M Cell Cycle Arrest and Apoptosis in MIA PaCa-2 Cells

door Du, Lin, Risinger, April L., King, Jarrod B., Powell, Douglas R., Cichewicz, Robert H.
Gepubliceerd in 2014

Targeting mosquito FREP1 with a fungal metabolite blocks malaria transmission

door Niu, Guodong, Wang, Bin, Zhang, Genwei, King, Jarrod B., Cichewicz, Robert H., Li, Jun
Gepubliceerd in Sci Rep (2015)

Leveraging Peptaibol Biosynthetic Promiscuity for Next-Generation Antiplasmodial Therapeutics

door Lee, Jin Woo, Collins, Jennifer E., Wendt, Karen L., Chakrabarti, Debopam, Cichewicz, Robert H.
Gepubliceerd in J Nat Prod (2021)

Secondary Metabolites from an Algicolous Aspergillus versicolor Strain

door Miao, Feng-Ping, Li, Xiao-Dong, Liu, Xiang-Hong, Cichewicz, Robert H., Ji, Nai-Yun
Gepubliceerd in 2012

Spiro Fused Diterpene-Indole Alkaloids from a Creek-Bottom-Derived Aspergillus terreus

door Cai, Shengxin, Du, Lin, Gerea, Alexandra L., King, Jarrod B., You, Jianlan, Cichewicz, Robert H.
Gepubliceerd in 2013

Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Trip...

door Kil, Yun-Seo, Risinger, April L., Petersen, Cora L., Mooberry, Susan L., Cichewicz, Robert H.
Gepubliceerd in J Nat Prod (2020)

Growth Inhibition of Colon Cancer and Melanoma Cells by Versiol Derivatives from a Paraconiothyrium sp.

door Cho, Namki, Ransom, Tanya T., Sigmund, Janet, Tran, Trong, Cichewicz, Robert H., Goetz, Michael, Beutler, John A.
Gepubliceerd in J Nat Prod (2017)