Microsecond molecular dynamics simulation of Aβ(42) and identification of a novel dual inhibitor of Aβ(42) aggregation and BACE1 activity

Por Wang, Yuan-yuan, Li, Li, Chen, Tian-tian, Chen, Wu-yan, Xu, Ye-chun
Publicado em 2013

Iron dysregulates APP processing accompanying with sAPPα cellular retention and β-secretase inhibition in rat cortical neurons

Por Chen, Yu-ting, Chen, Wu-yan, Huang, Xiao-tian, Xu, Ye-chun, Zhang, Hai-yan
Publicado no Acta Pharmacol Sin (2018)

L655,240, acting as a competitive BACE1 inhibitor, efficiently decreases β-amyloid peptide production in HEK293-APPswe cells

Por Lu, Qin, Chen, Wu-yan, Zhu, Zhi-yuan, Chen, Jing, Xu, Ye-chun, Kaewpet, Morakot, Rukachaisirikul, Vatcharin, Chen, Li-li, Shen, Xu
Publicado em 2012