APR-246/PRIMA-1(MET) inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase

Por Peng, X, Zhang, M-Q-Z, Conserva, F, Hosny, G, Selivanova, G, Bykov, V J N, Arnér, E S J, Wiman, K G
Publicado em 2013

APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells

Por Mohell, N, Alfredsson, J, Fransson, Å, Uustalu, M, Byström, S, Gullbo, J, Hallberg, A, Bykov, V J N, Björklund, U, Wiman, K G
Publicado no Cell Death Dis (2015)