Discovery of GSK2193874: An Orally Active, Potent, and Selective Blocker of Transient Receptor Potential Vanilloid 4

Por Cheung, Mui, Bao, Weike, Behm, David J., Brooks, Carl A., Bury, Michael J., Dowdell, Sarah E., Eidam, Hilary S., Fox, Ryan M., Goodman, Krista B., Holt, Dennis A., Lee, Dennis, Roethke, Theresa J., Willette, Robert N., Xu, Xiaoping, Ye, Guosen, Thorneloe, Kevin S.
Publicado no ACS Med Chem Lett (2017)

Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel

Por Haile, Pamela A., Casillas, Linda N., Bury, Michael J., Mehlmann, John F., Singhaus, Robert, Charnley, Adam K., Hughes, Terry V., DeMartino, Michael P., Wang, Gren Z., Romano, Joseph J., Dong, Xiaoyang, Plotnikov, Nikolay V., Lakdawala, Ami S., Convery, Maire A., Votta, Bartholomew J., Lipshutz, David B., Desai, Biva M., Swift, Barbara, Capriotti, Carol A., Berger, Scott B., Mahajan, Mukesh K., Reilly, Michael A., Rivera, Elizabeth J., Sun, Helen H., Nagilla, Rakesh, LePage, Carol, Ouellette, Michael T., Totoritis, Rachel D., Donovan, Brian T., Brown, Barry S., Chaudhary, Khuram W., Gough, Peter J., Bertin, John, Marquis, Robert W.
Publicado no ACS Med Chem Lett (2018)