Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection

Autor Lampi, Yulia, Van Looveren, Dominique, Vranckx, Lenard S., Thiry, Irina, Bornschein, Simon, Debyser, Zeger, Gijsbers, Rik
Vydáno v Sci Rep (2019)

Gain-of-function mutation in IFIH1 can cause both aicardi-goutières syndrome and systemic lupus erythematosus with IgA-deficiency

Autor Van Eyck, Lien, De Somer, Lien, Pombal, Diana, Bornschein, Simon, de Zegher, Francis, Liston, Adrian, Wouters, Carine
Vydáno 2014

Malt1 self‐cleavage is critical for regulatory T cell homeostasis and anti‐tumor immunity in mice

Autor Baens, Mathijs, Stirparo, Rocco, Lampi, Youlia, Verbeke, Delphine, Vandepoel, Roel, Cools, Jan, Marynen, Peter, de Bock, Charles E., Bornschein, Simon
Vydáno v Eur J Immunol (2018)

The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells

Autor Brajic, Aleksandra, Franckaert, Dean, Burton, Oliver, Bornschein, Simon, Calvanese, Anna L., Demeyer, Sofie, Cools, Jan, Dooley, James, Schlenner, Susan, Liston, Adrian
Vydáno v Front Immunol (2018)

Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL

Autor Degryse, Sandrine, Bornschein, Simon, de Bock, Charles E., Leroy, Emilie, Vanden Bempt, Marlies, Demeyer, Sofie, Jacobs, Kris, Geerdens, Ellen, Gielen, Olga, Soulier, Jean, Harrison, Christine J., Constantinescu, Stefan N., Cools, Jan
Vydáno v Blood (2018)

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

Autor Vanden Bempt, Marlies, Demeyer, Sofie, Broux, Michaël, De Bie, Jolien, Bornschein, Simon, Mentens, Nicole, Vandepoel, Roel, Geerdens, Ellen, Radaelli, Enrico, Bornhauser, Beat C., Kulozik, Andreas E., Meijerink, Jules P., Bourquin, Jean-Pierre, de Bock, Charles E., Cools, Jan
Vydáno v Cancer Cell (2018)

A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

Autor Verboom, Karen, Van Loocke, Wouter, Volders, Pieter-Jan, Decaesteker, Bieke, Cobos, Francisco Avila, Bornschein, Simon, de Bock, Charles E., Atak, Zeynep Kalender, Clappier, Emmanuelle, Aerts, Stein, Cools, Jan, Soulier, Jean, Taghon, Tom, Van Vlierberghe, Pieter, Vandesompele, Jo, Speleman, Frank, Durinck, Kaat
Vydáno v Haematologica (2018)

The T-cell leukemia associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling

Autor Girardi, Tiziana, Vereecke, Stijn, Sulima, Sergey O., Khan, Yousuf, Fancello, Laura, Briggs, Joseph W., Schwab, Claire, de Beeck, Joyce Op, Verbeeck, Jelle, Royaert, Jonathan, Geerdens, Ellen, Vicente, Carmen, Bornschein, Simon, Harrison, Christine J., Meijerink, Jules P., Cools, Jan, Dinman, Jonathan D., Kampen, Kim R., De Keersmaecker, Kim
Vydáno v Leukemia (2017)