Function, Regulation and Biological Roles of PI3Kγ Variants

Por Nürnberg, Bernd, Beer-Hammer, Sandra
Publicado no Biomolecules (2019)

The orphan adapter protein SLY1 as a novel anti-apoptotic protein required for thymocyte development

Por Reis, Bernhard, Pfeffer, Klaus, Beer-Hammer, Sandra
Publicado em 2009

p87 and p101 Subunits Are Distinct Regulators Determining Class I(B) Phosphoinositide 3-Kinase (PI3K) Specificity

Por Shymanets, Aliaksei, Prajwal, Bucher, Kirsten, Beer-Hammer, Sandra, Harteneck, Christian, Nürnberg, Bernd
Publicado em 2013

Immunoinhibitory Adapter Protein Src Homology Domain 3 Lymphocyte Protein 2 (SLy2) Regulates Actin Dynamics and B Cell Spreading

Por von Holleben, Max, Gohla, Antje, Janssen, Klaus-Peter, Iritani, Brian M., Beer-Hammer, Sandra
Publicado em 2011

RXFP1 Receptor Activation by Relaxin-2 Induces Vascular Relaxation in Mice via a Gα(i2)-Protein/PI3Kß/γ/Nitric Oxide-Coupled Pathway

Por Lian, Xiaoming, Beer-Hammer, Sandra, König, Gabriele M., Kostenis, Evi, Nürnberg, Bernd, Gollasch, Maik
Publicado no Front Physiol (2018)

SLy2‐deficiency promotes B‐1 cell immunity and triggers enhanced production of IgM and IgG(2) antibodies against pneumococcal vaccine

Por Jaufmann, Jennifer, Tümen, Leyla, Schmitt, Fee, Schäll, Daniel, von Holleben, Max, Beer‐Hammer, Sandra
Publicado no Immun Inflamm Dis (2020)

Neuroprotective, Neurogenic, and Amyloid Beta Reducing Effect of a Novel Alpha 2-Adrenoblocker, Mesedin, on Astroglia and Neuronal Progenitors upon Hypoxia and Glutamate Exposure

Por Melkonyan, Magda M., Hunanyan, Lilit, Lourhmati, Ali, Layer, Nikolas, Beer-Hammer, Sandra, Yenkoyan, Konstantin, Schwab, Matthias, Danielyan, Lusine
Publicado no Int J Mol Sci (2017)

p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation.

Por Benedikt Mothes, Kirsten Bucher, Susanne Ammon-Treiber, Matthias Schwab, Roland P Piekorz, Emilio Hirsch, Bernd Nürnberg, Sandra Beer-Hammer
Publicado em 2016-01-01

p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation

Por Mothes, Benedikt, Bucher, Kirsten, Ammon-Treiber, Susanne, Schwab, Matthias, Piekorz, Roland P., Hirsch, Emilio, Nürnberg, Bernd, Beer-Hammer, Sandra
Publicado no PLoS One (2016)

Correction: p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation

Por Mothes, Benedikt, Bucher, Kirsten, Ammon-Treiber, Susanne, Schwab, Matthias, Piekorz, Roland P., Hirsch, Emilio, Nürnberg, Bernd, Beer-Hammer, Sandra
Publicado no PLoS One (2016)

Deficiency of PI3-Kinase catalytic isoforms p110γ and p110δ in mice enhances the IL-17/G-CSF axis and induces neutrophilia

Por Bucher, Kirsten, Schmitt, Fee, Mothes, Benedikt, Blumendeller, Carolin, Schäll, Daniel, Piekorz, Roland, Hirsch, Emilio, Nürnberg, Bernd, Beer-Hammer, Sandra
Publicado no Cell Commun Signal (2017)

mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo

Por Zeyer, Franziska, Mothes, Benedikt, Will, Clara, Carevic, Melanie, Rottenberger, Jennifer, Nürnberg, Bernd, Hartl, Dominik, Handgretinger, Rupert, Beer-Hammer, Sandra, Kormann, Michael S. D.
Publicado no PLoS One (2016)

Correction: mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo

Por Zeyer, Franziska, Mothes, Benedikt, Will, Clara, Carevic, Melanie, Rottenberger, Jennifer, Nürnberg, Bernd, Hartl, Dominik, Handgretinger, Rupert, Beer-Hammer, Sandra, Kormann, Michael S. D.
Publicado no PLoS One (2018)

Murine Guanylate Binding Protein 2 (mGBP2) controls Toxoplasma gondii replication

Por Degrandi, Daniel, Kravets, Elisabeth, Konermann, Carolin, Beuter-Gunia, Cornelia, Klümpers, Verena, Lahme, Sarah, Rasch, Eva, Mausberg, Anne K., Beer-Hammer, Sandra, Pfeffer, Klaus
Publicado em 2013

Staphylococcus aureus PSM peptides modulate dendritic cell functions and increase in vitro priming of regulatory T cells()

Por Schreiner, Jens, Kretschmer, Dorothee, Klenk, Juliane, Otto, Michael, Bühring, Hans-Jörg, Stevanovic, Stefan, Wang, Ji Ming, Beer-Hammer, Sandra, Peschel, Andreas, Autenrieth, Stella E.
Publicado em 2013

Dataset on the activation of Müller cells through macrophages upon hypoxia in the retina

Por Nürnberg, Christina, Kociok, Norbert, Brockmann, Claudia, Lischke, Timo, Crespo-Garcia, Sergio, Reichhart, Nadine, Wolf, Susanne, Baumgrass, Ria, Eming, Sabine A., Beer-Hammer, Sandra, Joussen, Antonia M.
Publicado no Data Brief (2017)

Gα(i2)- and Gα(i3)-Deficient Mice Display Opposite Severity of Myocardial Ischemia Reperfusion Injury

Por Köhler, David, Devanathan, Vasudharani, Bernardo de Oliveira Franz, Claudia, Eldh, Therese, Novakovic, Ana, Roth, Judith M., Granja, Tiago, Birnbaumer, Lutz, Rosenberger, Peter, Beer-Hammer, Sandra, Nürnberg, Bernd
Publicado em 2014

Platelet G(i) protein Gα(i2) is an essential mediator of thrombo-inflammatory organ damage in mice

Por Devanathan, Vasudharani, Hagedorn, Ina, Köhler, David, Pexa, Katja, Cherpokova, Deya, Kraft, Peter, Singh, Madhurendra, Rosenberger, Peter, Stoll, Guido, Birnbaumer, Lutz, Piekorz, Roland P., Beer-Hammer, Sandra, Nieswandt, Bernhard, Nürnberg, Bernd
Publicado no Proc Natl Acad Sci U S A (2015)

Intranasal Losartan Decreases Perivascular Beta Amyloid, Inflammation, and the Decline of Neurogenesis in Hypertensive Rats

Por Drews, Henning J., Yenkoyan, Konstantin, Lourhmati, Ali, Buadze, Marine, Kabisch, Daniela, Verleysdonk, Stephan, Petschak, Stefan, Beer-Hammer, Sandra, Davtyan, Tigran, Frey, William H., Gleiter, Christoph H., Schwab, Matthias, Danielyan, Lusine
Publicado no Neurotherapeutics (2019)

Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association

Por Kukuk, Laura, Dingley, Andrew J., Granzin, Joachim, Nagel-Steger, Luitgard, Thiagarajan-Rosenkranz, Pallavi, Ciupka, Daniel, Hänel, Karen, Batra-Safferling, Renu, Pacheco, Victor, Stoldt, Matthias, Pfeffer, Klaus, Beer-Hammer, Sandra, Willbold, Dieter, Koenig, Bernd W.
Publicado no Sci Rep (2019)