Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions

af Tuttle, Jamison B., Anderson, Marie, Bechle, Bruce M., Campbell, Brian M., Chang, Cheng, Dounay, Amy B., Evrard, Edelweiss, Fonseca, Kari R., Gan, Xinmin, Ghosh, Somraj, Horner, Weldon, James, Larry C., Kim, Ji-Young, McAllister, Laura A., Pandit, Jayvardhan, Parikh, Vinod D., Rago, Brian J., Salafia, Michelle A., Strick, Christine A., Zawadzke, Laura E., Verhoest, Patrick R.
Udgivet 2012

Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia

af Dounay, Amy B., Anderson, Marie, Bechle, Bruce M., Campbell, Brian M., Claffey, Michelle M., Evdokimov, Artem, Evrard, Edelweiss, Fonseca, Kari R., Gan, Xinmin, Ghosh, Somraj, Hayward, Matthew M., Horner, Weldon, Kim, Ji-Young, McAllister, Laura A., Pandit, Jayvardhan, Paradis, Vanessa, Parikh, Vinod D., Reese, Matthew R., Rong, SuoBao, Salafia, Michelle A., Schuyten, Katherine, Strick, Christine A., Tuttle, Jamison B., Valentine, James, Wang, Hong, Zawadzke, Laura E., Verhoest, Patrick R.
Udgivet 2012