Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption

od Bagal, Sharan K., Bungay, Peter J.
Wydane 2012

Voltage gated sodium channels as drug discovery targets

od Bagal, Sharan K, Marron, Brian E, Owen, Robert M, Storer, R Ian, Swain, Nigel A
Wydane w Channels (Austin) (2015)

Discovery and Optimization of Selective Na(v)1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain

od Bagal, Sharan K., Bungay, Peter J., Denton, Stephen M., Gibson, Karl R., Glossop, Melanie S., Hay, Tanya L., Kemp, Mark I., Lane, Charlotte A. L., Lewis, Mark L., Maw, Graham N., Million, William A., Payne, C. Elizabeth, Poinsard, Cedric, Rawson, David J., Stammen, Blanda L., Stevens, Edward B., Thompson, Lisa R.
Wydane w ACS Med Chem Lett (2015)

A novel selective and orally bioavailable Na(v)1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability

od Payne, Claire Elizabeth, Brown, Adam R, Theile, Jonathon W, Loucif, Alexandre J C, Alexandrou, Aristos J, Fuller, Mathew D, Mahoney, John H, Antonio, Brett M, Gerlach, Aaron C, Printzenhoff, David M, Prime, Rebecca L, Stockbridge, Gillian, Kirkup, Anthony J, Bannon, Anthony W, England, Steve, Chapman, Mark L, Bagal, Sharan, Roeloffs, Rosemarie, Anand, Uma, Anand, Praveen, Bungay, Peter J, Kemp, Mark, Butt, Richard P, Stevens, Edward B
Wydane w Br J Pharmacol (2015)