Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption

av Bagal, Sharan K., Bungay, Peter J.
Publicerad 2012

Voltage gated sodium channels as drug discovery targets

av Bagal, Sharan K, Marron, Brian E, Owen, Robert M, Storer, R Ian, Swain, Nigel A
I publikationen Channels (Austin) (2015)

Discovery and Optimization of Selective Na(v)1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain

av Bagal, Sharan K., Bungay, Peter J., Denton, Stephen M., Gibson, Karl R., Glossop, Melanie S., Hay, Tanya L., Kemp, Mark I., Lane, Charlotte A. L., Lewis, Mark L., Maw, Graham N., Million, William A., Payne, C. Elizabeth, Poinsard, Cedric, Rawson, David J., Stammen, Blanda L., Stevens, Edward B., Thompson, Lisa R.
I publikationen ACS Med Chem Lett (2015)

A novel selective and orally bioavailable Na(v)1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability

av Payne, Claire Elizabeth, Brown, Adam R, Theile, Jonathon W, Loucif, Alexandre J C, Alexandrou, Aristos J, Fuller, Mathew D, Mahoney, John H, Antonio, Brett M, Gerlach, Aaron C, Printzenhoff, David M, Prime, Rebecca L, Stockbridge, Gillian, Kirkup, Anthony J, Bannon, Anthony W, England, Steve, Chapman, Mark L, Bagal, Sharan, Roeloffs, Rosemarie, Anand, Uma, Anand, Praveen, Bungay, Peter J, Kemp, Mark, Butt, Richard P, Stevens, Edward B
I publikationen Br J Pharmacol (2015)