AMD3100 is a potent antagonist at CXCR4(R334X), a hyperfunctional mutant chemokine receptor and cause of WHIM syndrome

Por McDermott, David H, Lopez, Joseph, Deng, Francis, Liu, Qian, Ojode, Teresa, Chen, Haoqian, Ulrick, Jean, Kwatemaa, Nana, Kelly, Corin, Anaya-O’Brien, Sandra, Garofalo, Mary, Marquesen, Martha, Hilligoss, Dianne, DeCastro, Rosamma, Malech, Harry L, Murphy, Philip M
Publicado em 2011

WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4

Por Liu, Qian, Chen, Haoqian, Ojode, Teresa, Gao, Xiangxi, Anaya-O'Brien, Sandra, Turner, Nicholas A., Ulrick, Jean, DeCastro, Rosamma, Kelly, Corin, Cardones, Adela R., Gold, Stuart H., Hwang, Eugene I., Wechsler, Daniel S., Malech, Harry L., Murphy, Philip M., McDermott, David H.
Publicado em 2012

The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome

Por McDermott, David H., Liu, Qian, Ulrick, Jean, Kwatemaa, Nana, Anaya-O'Brien, Sandra, Penzak, Scott R., Filho, Joao Oliveira, Priel, Debra A. Long, Kelly, Corin, Garofalo, Mary, Littel, Patricia, Marquesen, Martha M., Hilligoss, Diane, DeCastro, Rosamma, Fleisher, Thomas A., Kuhns, Douglas B., Malech, Harry L., Murphy, Philip M.
Publicado em 2011

CXCR4/IgG-expressing plasma cells are associated with human gastrointestinal tissue inflammation

Por Buckner, Clarisa M., Moir, Susan, Kardava, Lela, Ho, Jason, Santich, Brian H., Kim, Leo Jin Young, Funk, Emily K., Nelson, Amy K., Winckler, Britanny, Chairez, Cheryl L., Theobald-Whiting, Narda L., Anaya-O’Brien, Sandra, Alimchandani, Meghna, Quezado, Martha M., Yao, Michael D., Kovacs, Joseph A., Chun, Tae-Wook, Fauci, Anthony S., Malech, Harry L., De Ravin, Suk See
Publicado em 2013

A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor

Por McDermott, David H., Liu, Qian, Velez, Daniel, Lopez, Lizbeeth, Anaya-O’Brien, Sandra, Ulrick, Jean, Kwatemaa, Nana, Starling, Judy, Fleisher, Thomas A., Priel, Debra A. Long, Merideth, Melissa A., Giuntoli, Robert L., Evbuomwan, Moses O., Littel, Patricia, Marquesen, Martha M., Hilligoss, Dianne, DeCastro, Rosamma, Grimes, George J., Hwang, Samuel T., Pittaluga, Stefania, Calvo, Katherine R., Stratton, Pamela, Cowen, Edward W., Kuhns, Douglas B., Malech, Harry L., Murphy, Philip M.
Publicado em 2014

Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency

Por De Ravin, Suk See, Wu, Xiaolin, Moir, Susan, Kardava, Lela, Anaya-O’Brien, Sandra, Kwatemaa, Nana, Littel, Patricia, Theobald, Narda, Choi, Uimook, Su, Ling, Marquesen, Martha, Hilligoss, Dianne, Lee, Janet, Buckner, Clarissa M., Zarember, Kol A., O’Connor, Geraldine, McVicar, Daniel, Kuhns, Douglas, Throm, Robert E., Zhou, Sheng, Notarangelo, Luigi D., Hanson, I. Celine, Cowan, Mort J., Kang, Elizabeth, Hadigan, Coleen, Meagher, Michael, Gray, John T., Sorrentino, Brian P., Malech, Harry L.
Publicado no Sci Transl Med (2016)

Pulmonary Nontuberculous Mycobacterial Disease: Prospective Study of a Distinct Preexisting Syndrome

Por Kim, Richard D., Greenberg, David E., Ehrmantraut, Mary E., Guide, Shireen V., Ding, Li, Shea, Yvonne, Brown, Margaret R., Chernick, Milica, Steagall, Wendy K., Glasgow, Connie G., Lin, JingPing, Jolley, Clara, Sorbara, Lynn, Raffeld, Mark, Hill, Suvimol, Avila, Nilo, Sachdev, Vandana, Barnhart, Lisa A., Anderson, Victoria L., Claypool, Reginald, Hilligoss, Dianne M., Garofalo, Mary, Fitzgerald, Alan, Anaya-O'Brien, Sandra, Darnell, Dirk, DeCastro, Rosamma, Menning, Heather M., Ricklefs, Stacy M., Porcella, Stephen F., Olivier, Kenneth N., Moss, Joel, Holland, Steven M.
Publicado em 2008