A Cell-Level Systems PK-PD Model to Characterize In Vivo Efficacy of ADCs

Por Aman P. Singh, Leiming Guo, Ashwni Verma, Gloria Gao-Li Wong, Dhaval K. Shah
Publicado em 2019-02-01

Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model

Por Aman P. Singh, Xirong Zheng, Xiefan Lin-Schmidt, Wenbo Chen, Thomas J. Carpenter, Alice Zong, Weirong Wang, Donald L. Heald
Publicado em 2020-01-01

Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives

Por Mingming Zhang, Allan M. Prior, Marcus M. Maddox, Wan-Jou Shen, Kirk E. Hevener, David F. Bruhn, Robin B. Lee, Aman P. Singh, Justin Reinicke, Charles J. Simmons, Julian G. Hurdle, Richard E. Lee, Dianqing Sun
Publicado em 2018-12-01