Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation

Por Agabiti, Sherry S, Li, Jin, Wiemer, Andrew J
Publicado no Cell Death Dis (2017)

Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation

Por Agabiti, Sherry S., Liang, Yilan, Wiemer, Andrew J.
Publicado no Mol Membr Biol (2016)

Phosphinophosphonates and their tris-pivaloyloxymethyl prodrugs reveal a negatively cooperative butyrophilin activation mechanism

Por Shippy, Rebekah R., Lin, Xiaochen, Agabiti, Sherry S., Li, Jin, Zangari, Brendan M., Foust, Benjamin J., Poe, Michael M., Hsiao, Chia-Hung Christine, Vinogradova, Olga, Wiemer, David F., Wiemer, Andrew J.
Publicado no J Med Chem (2017)