Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine

Por Adema, Auke D, Floor, Karijn, Smid, Kees, Honeywell, Richard J, Scheffer, George L, Jansen, Gerrit, Peters, Godefridus J
Publicado no Springerplus (2014)

Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126

Por Adema, Auke D., Smid, Kees, Losekoot, Nienke, Honeywell, Richard J., Verheul, Henk M., Myhren, Finn, Sandvold, Marit L., Peters, Godefridus J.
Publicado em 2011

Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models

Por Bergman, Andries M., Adema, Auke D., Balzarini, Jan, Bruheim, Skjalg, Fichtner, Iduna, Noordhuis, Paul, Fodstad, Øystein, Myhren, Finn, Sandvold, Marit L., Hendriks, Hans R., Peters, Godefridus J.
Publicado em 2010