Resultados da pesquisa - safety after arm phase role

Pesquisas alternativas:
phase role » phase rule (Expandir a Pesquisa), phase route (Expandir a Pesquisa), phase whole (Expandir a Pesquisa)
after arm » after warm (Expandir a Pesquisa), after harm (Expandir a Pesquisa), after art (Expandir a Pesquisa)
arm phase » from phase (Expandir a Pesquisa), m phase (Expandir a Pesquisa)

21

Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine

Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine

Por Goh, Gerald, Schmid, Ramona, Guiver, Kelly, Arpornwirat, Wichit, Chitapanarux, Imjai, Ganju, Vinod, Im, Seock-Ah, Kim, Sung-Bae, Dechaphunkul, Arunee, Maneechavakajorn, Jedzada, Spector, Neil, Yau, Thomas, Afrit, Mehdi, Ahmed, Slim Ben, Johnston, Stephen R., Gibson, Neil, Uttenreuther-Fischer, Martina, Herrero, Javier, Swanton, Charles
Publicado no PLoS Med (2016)

“... performed an open-label, single-arm phase II clinical trial (ClinicalTrials.gov NCT01325428) to investigate...”
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22

Efficacy, safety, and tolerability of lacosamide in patients with gain-of-function Na(v)1.7 mutation-related small fiber neuropathy: study protocol of a randomized controlled trial–the LENSS study

Efficacy, safety, and tolerability of lacosamide in patients with gain-of-function Na(v)1.7...

Por de Greef, Bianca T. A., Merkies, Ingemar S. J., Geerts, Margot, Faber, Catharina G., Hoeijmakers, Janneke G. J.
Publicado no Trials (2016)

“...: The Lacosamide-Efficacy-‘N’-Safety in Small fiber neuropathy (LENSS) study is a randomized, double-blind, placebo...”
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23

Randomized phase II trial of docetaxel with or without PSA-TRICOM vaccine in patients with castrate-resistant metastatic prostate cancer: A trial of the ECOG-ACRIN cancer research group (E1809)

Randomized phase II trial of docetaxel with or without PSA-TRICOM vaccine in patients with castrate...

Por McNeel, Douglas G, Chen, Yu-Hui, Gulley, James L, Dwyer, Alexander J, Madan, Ravi A, Carducci, Michael A, DiPaola, Robert S
Publicado no Hum Vaccin Immunother (2015)

“... and fowlpox viral vectors encoding PSA, is currently being evaluated in a registration phase III multinational...”
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24

An Australian translational Study to evaluate the prognostic role of inflammatory markers in patients with metastatic ColorEctal caNcer Treated with bevacizumab (Avastin™) [ASCENT]

An Australian translational Study to evaluate the prognostic role of inflammatory markers...

Por Clarke, Stephen, Burge, Matt, Cordwell, Cassandra, Gibbs, Peter, Reece, William, Tebbutt, Niall
Publicado em 2013

“... characterise the safety of bevacizumab following treatment initiation, and when continued after progression...”
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25

Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma – CapRI: study protocol [ISRCTN62866759]

Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external...

Por Knaebel, HP, Märten, A, Schmidt, J, Hoffmann, K, Seiler, C, Lindel, K, Schmitz-Winnenthal, H, Fritz, S, Herrmann, T, Goldschmidt, H, Mansmann, U, Debus, J, Diehl, V, Büchler, MW
Publicado em 2005

“..., randomised multi-centre phase III trial. Patients in study arm A will be treated as outpatients with 5...”
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26

Study protocol of a multicenter phase III randomized controlled trial investigating the efficiency of the combination of neoadjuvant chemotherapy (NAC) and neoadjuvant laparoscopic intraperitoneal hyperthermic chemotherapy (NLHIPEC) followed by R0 gastrectomy with intraoperative HIPEC for advanced gastric cancer (AGC): dragon II trial

Study protocol of a multicenter phase III randomized controlled trial investigating the efficiency...

Por Beeharry, Maneesh Kumarsing, Ni, Zhen-Tian, Yang, Zhong Yin, Zheng, Ya Nan, Feng, Run Hua, Liu, Wen-Tao, Yan, Chao, Yao, Xue Xin, Li, Chen, Yan, Min, Zhu, Zheng-Gang
Publicado no BMC Cancer (2020)

“... of treatment failure and disease recurrence. The role of hyperthermic intraperitoneal chemotherapy (HIPEC) has...”
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27

The promise of CAR T-cell therapy in aggressive B-cell lymphoma

The promise of CAR T-cell therapy in aggressive B-cell lymphoma

Por Nair, Ranjit, Neelapu, Sattva S.
Publicado no Best Pract Res Clin Haematol (2018)

“... of systemic therapy based on multicenter single-arm phase two clinical trials. Here, we will discuss...”
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28

P01.095 The use of TTFields for newly diagnosed GBM patients in Germany in routine clinical care (TIGER: TTFields in Germany in routine clinical care)

P01.095 The use of TTFields for newly diagnosed GBM patients in Germany in routine clinical care (TIGER: TTFields in Germany in routine clinical care)

Por Bähr, O, Tabatabai, G, Fietkau, R, Goldbrunner, R, Glas, M
Publicado no Neuro Oncol (2018)

“... has remained essentially unchanged since 2005 despite numerous clinical Phase 3 trials conducted...”
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29

Effect of PF-04634817, an Oral CCR2/5 Chemokine Receptor Antagonist, on Albuminuria in Adults with Overt Diabetic Nephropathy

Effect of PF-04634817, an Oral CCR2/5 Chemokine Receptor Antagonist, on Albuminuria in Adults with Overt Diabetic Nephropathy

Por Gale, Jeremy D., Gilbert, Steven, Blumenthal, Samuel, Elliott, Tom, Pergola, Pablo E., Goteti, Kosalaram, Scheele, Wim, Perros-Huguet, Christelle
Publicado no Kidney Int Rep (2018)

“...) activity, may play a role in the development and progression of diabetic nephropathy. PF-04634817 is a dual...”
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30

ATIM-09. CLINICAL TRIAL IN PROGRESS: A STUDY OF NEOADJUVANT AND ADJUVANT VB-111 FOR TREATMENT OF RECURRENT GBM

ATIM-09. CLINICAL TRIAL IN PROGRESS: A STUDY OF NEOADJUVANT AND ADJUVANT VB-111 FOR TREATMENT OF RECURRENT GBM

Por Cloughesy, Timothy, Butowski, Nicholas, Harats, Dror, Rachmilewitz Minei, Tamar, Wen, Patrick
Publicado no Neuro Oncol (2019)

“...: Neoadjuvant Arm: intravenous VB-111 prior to resection, and VB-111 every 6 weeks after resection. Adjuvant Arm...”
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31

Liquid Biopsy Testing Can Improve Selection of Advanced Non-Small-Cell Lung Cancer Patients to Rechallenge with Gefitinib

Liquid Biopsy Testing Can Improve Selection of Advanced Non-Small-Cell Lung Cancer Patients to Rechallenge with Gefitinib

Por Esposito Abate, Riziero, Pasquale, Raffaella, Sacco, Alessandra, Piccirillo, Maria Carmela, Morabito, Alessandro, Bidoli, Paolo, Finocchiaro, Giovanna, Chiari, Rita, Foltran, Luisa, Buosi, Roberta, Tiseo, Marcello, Giannetta, Laura, Battiloro, Ciro, Fasola, Gianpiero, Romano, Gianpiero, Ciuffreda, Libero, Frassoldati, Antonio, de Marinis, Filippo, Cappuzzo, Federico, Normanno, Nicola
Publicado no Cancers (Basel) (2019)

“...The ICARUS trial is a phase II, open label, multicenter, single arm study conducted to investigate...”
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32

Docetaxel-carboplatin in combination with erlotinib and/or bevacizumab in patients with non-small cell lung cancer

Docetaxel-carboplatin in combination with erlotinib and/or bevacizumab in patients with non-small cell lung cancer

Por Boutsikou, Eftimia, Kontakiotis, Theodoros, Zarogoulidis, Paul, Darwiche, Kaid, Eleptheriadou, Ellada, Porpodis, Konstantinos, Galaktidou, Grammati, Sakkas, Leonidas, Hohenforst-Schmidt, Wolfgang, Tsakiridis, Kosmas, Karaiskos, Theodoros, Zarogoulidis, Konstantinos
Publicado em 2013

“... in patients with non-squamous non-small cell lung cancer (NSCLC). We designed a four-arm Phase III trial...”
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33

$Ganetespib, a Novel Hsp90 Inhibitor in Patients With KRAS Mutated and Wild Type, Refractory Metastatic Colorectal Cancer$

Ganetespib, a Novel Hsp90 Inhibitor in Patients With KRAS Mutated and Wild Type, Refractory Metastatic Colorectal Cancer

Por Cercek, Andrea, Shia, Jinru, Gollub, Marc, Chou, Joanne F., Capanu, Marinela, Raasch, Pamela, Reidy-Lagunes, Diane, Proia, David A., Vakiani, Efsevia, Solit, David B., Saltz, Leonard B.
Publicado no Clin Colorectal Cancer (2014)

“... single-arm, Simon 2-stage, phase II trial for patients with chemotherapy-refractory, metastatic...”
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34

Stem Cell Therapy for Cirrhosis of Liver in Bangladesh: Specific Design Compatible for Developing Country

Stem Cell Therapy for Cirrhosis of Liver in Bangladesh: Specific Design Compatible for Developing Country

Por Al Mahtab, Mamun, MF Akbar, Sheikh, Begum, Masuda, Islam, Md. A, Rahim, Md. A, M Noor-E-Alam, Sheikh, Alam, Md. A, A Khondaker, Faiz, L Moben, Ahmed, Mohsena, Masuda, Khan, Md. Sakirul I, Huq, Md. Z, Munshi, Swati, Hoque, Ashraful, Haque, Sheikh A
Publicado no Euroasian J Hepatogastroenterol (2018)

“... and only 4 patients had ascites after 3 months. The positive role of stem cell therapy on ascites in LC...”
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35

Exposure-adjusted adverse events comparing blinatumomab with chemotherapy in advanced acute lymphoblastic leukemia

Exposure-adjusted adverse events comparing blinatumomab with chemotherapy in advanced acute lymphoblastic leukemia

Por Stein, Anthony S., Larson, Richard A., Schuh, Andre C., Stevenson, William, Lech-Maranda, Ewa, Tran, Qui, Zimmerman, Zachary, Kormany, William, Topp, Max S.
Publicado no Blood Adv (2018)

“..., as treatment exposure differed between the 2 arms, we conducted an exploratory safety analysis comparing...”
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36

20. Tocilizumab: is out of sight really out of mind?

20. Tocilizumab: is out of sight really out of mind?

Por Khalid, Salema, Smith, Richard, Cole, Zoe
Publicado no Rheumatol Adv Pract (2019)

“... patients randomised to the TCZ treatment arm were in remission after 12 months. Only half stayed...”
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37

Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study

Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study

Por Aroda, Vanita R., Knowler, William C., Crandall, Jill P., Perreault, Leigh, Edelstein, Sharon L., Jeffries, Susan L., Molitch, Mark E., Pi-Sunyer, Xavier, Darwin, Christine, Heckman-Stoddard, Brandy M., Temprosa, Marinella, Kahn, Steven E., Nathan, David M.
Publicado no Diabetologia (2017)

“... assessment of glycaemic, cardiometabolic, health economic, and safety outcomes. After an average follow-up...”
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38

miR-21 expression and clinical outcome in locally advanced pancreatic cancer: exploratory analysis of the pancreatic cancer Erbitux, radiotherapy and UFT (PERU) trial

miR-21 expression and clinical outcome in locally advanced pancreatic cancer: exploratory analysis of the pancreatic cancer Erbitux, radiotherapy and UFT (PERU) trial

Por Khan, Khurum, Cunningham, David, Peckitt, Clare, Barton, Sarah, Tait, Diana, Hawkins, Maria, Watkins, David, Starling, Naureen, Rao, Sheela, Begum, Ruwaida, Thomas, Janet, Oates, Jacqui, Guzzardo, Vincenza, Fassan, Matteo, Braconi, Chiara, Chau, Ian
Publicado no Oncotarget (2016)

“... achieving disease control and being randomised to arms A (n:7) and B (n:6). After a median follow-up of 61.2...”
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39

Liquid Biopsy Testing Can Improve Selection of Advanced Non-Small-Cell Lung Cancer Patients to Rechallenge with Gefitinib

Liquid Biopsy Testing Can Improve Selection of Advanced Non-Small-Cell Lung Cancer Patients to Rechallenge with Gefitinib

Por Riziero Esposito Abate, Raffaella Pasquale, Alessandra Sacco, Maria Carmela Piccirillo, Alessandro Morabito, Paolo Bidoli, Giovanna Finocchiaro, Rita Chiari, Luisa Foltran, Roberta Buosi, Marcello Tiseo, Laura Giannetta, Ciro Battiloro, Gianpiero Fasola, Gianpiero Romano, Libero Ciuffreda, Antonio Frassoldati, Filippo de Marinis, Federico Cappuzzo, Nicola Normanno
Publicado em 2019-09-01

“...The ICARUS trial is a phase II, open label, multicenter, single arm study conducted to investigate...”
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40

Treatment of Cancer-Associated Thrombosis: Beyond HOKUSAI

Treatment of Cancer-Associated Thrombosis: Beyond HOKUSAI

Por Mahé, Isabelle, Elalamy, Ismaïl, Gerotziafas, Grigoris T., Girard, Philippe
Publicado no TH Open (2019)

“... suggested that DOACs' efficacy and safety profile were comparable to those of LMWHs. In the randomized...”
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