Resultados da pesquisa - (( j a amp can new ) OR ((( a nagy clamp a new ) OR ( j led con ((canada ne) OR (canada new)) ))))

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led » lead (Expandir a Pesquisa)

21

AMPK activation and metabolic reprogramming by tamoxifen through estrogen receptor-independent mechanisms suggests new uses for this therapeutic modality in cancer treatment

AMPK activation and metabolic reprogramming by tamoxifen through estrogen receptor-independent mechanisms suggests new uses for this therapeutic modality in cancer treatment

Por Daurio, Natalie A., Tuttle, Stephen W., Worth, Andrew J., Song, Ethan Y., Davis, Julianne M., Snyder, Nathaniel W., Blair, Ian A., Koumenis, Constantinos
Publicado no Cancer Res (2016)

“... (ER) positive breast cancer, yet a large body of clinical and preclinical data indicates...”
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22

Fosfomycin: A First-Line Oral Therapy for Acute Uncomplicated Cystitis

Fosfomycin: A First-Line Oral Therapy for Acute Uncomplicated Cystitis

Por Zhanel, George G., Walkty, Andrew J., Karlowsky, James A.
Publicado no Can J Infect Dis Med Microbiol (2016)

“...Fosfomycin is a new agent to Canada approved for the treatment of acute uncomplicated cystitis (AUC...”
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23

Protein synthesis during acquisition of long-term facilitation is needed for the persistent loss of regulatory subunits of the Aplysia cAMP-dependent protein kinase.

Protein synthesis during acquisition of long-term facilitation is needed for the persistent loss of regulatory subunits of the Aplysia cAMP-dependent protein kinase.

Por Bergold, P J, Sweatt, J D, Winicov, I, Weiss, K R, Kandel, E R, Schwartz, J H
Publicado em 1990

“.... Increasing intracellular cAMP with a permeable analog of cAMP together with the phosphodiesterase inhibitor...”
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24

Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies

Characterization of a Pachymedusa dacnicolor–Sauvagine Analog as a New High-Affinity Radioligand for Corticotropin-Releasing Factor Receptor Studies

Por Perrin, Marilyn H., Tan, Laura A., Vaughan, Joan M., Lewis, Kathy A., Donaldson, Cynthia J., Miller, Charleen, Erchegyi, Judit, Rivier, Jean E., Sawchenko, Paul E.
Publicado no J Pharmacol Exp Ther (2015)

“... ligands. These assays depend on stable, high-affinity CRF analogs that can be labeled, purified...”
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25

Spider Silk Biomimetics Programs to Inform the Development of New Wearable Technologies

Spider Silk Biomimetics Programs to Inform the Development of New Wearable Technologies

Por Sean J. Blamires, Patrick T. Spicer, Patricia J. Flanagan
Publicado em 2020-02-01

“... petrochemicals. These have negative effects on the natural environment as a consequence of the manufacturing...”
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26

A new method for retrieval of the extinction coefficient of water clouds by using the tail of the CALIOP signal

A new method for retrieval of the extinction coefficient of water clouds by using the tail of the CALIOP signal

Por J. Li, Y. Hu, J. Huang, K. Stamnes, Y. Yi, S. Stamnes
Publicado em 2011-03-01

“... in extinction coefficient is about 13.4%. An important advantage of the new method is that it can be used...”
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27

Evaluation of a prototype electronic personal health record for patients with idiopathic thrombocytopenic purpura

Evaluation of a prototype electronic personal health record for patients with idiopathic thrombocytopenic purpura

Por Chiche L, Brescianini A, Mancini J, Servy H, Dur, JM
Publicado em 2012-10-01

“... records may also offer a tool for capturing patients&#39; reported outcomes, thus enhancing...”
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28

The EPAC–Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability

The EPAC–Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability

Por Ramos, Carla J., Lin, Chengmao, Liu, Xuwen, Antonetti, David A.
Publicado no J Biol Chem (2018)

“... vascular permeability and restore the blood–retinal barrier (BRB) may lead to new therapies. The cAMP...”
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29

Pilot Testing Of A Brief Pre-Consultation Screener For Improving The Identification And Discussion Of Medication Adherence In Routine Consultations

Pilot Testing Of A Brief Pre-Consultation Screener For Improving The Identification And Discussion Of Medication Adherence In Routine Consultations

Por Weinman J, Ali I, Hodgkinson A, Canfield M, Jackson C
Publicado em 2019-11-01

“... by examining the value of a new brief medicines use screener in helping patients to identify and discuss...”
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30

Long-term effect of neuronal nitric oxide synthase over-expression on cardiac neurotransmission mediated by a lentiviral vector

Long-term effect of neuronal nitric oxide synthase over-expression on cardiac neurotransmission mediated by a lentiviral vector

Por Wang, Lijun, Li, Dan, Dawson, Tom A, Paterson, David J
Publicado em 2009

“...-expression mediated by a lentiviral vector can modulate sympatho-vagal control of cardiac excitability...”
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31

Cell-type-specific regulation of the human tumor necrosis factor alpha gene in B cells and T cells by NFATp and ATF-2/JUN.

Cell-type-specific regulation of the human tumor necrosis factor alpha gene in B cells and T cells by NFATp and ATF-2/JUN.

Por Tsai, E Y, Yie, J, Thanos, D, Goldfeld, A E
Publicado em 1996

“..., induction of TNF-alpha gene transcription can be blocked by the immunosuppressants cyclosporin A and FK506...”
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32

Effects of storm events on the shelf-to-basin sediment transport in the southwestern end of the Gulf of Lions (Northwestern Mediterranean)

Effects of storm events on the shelf-to-basin sediment transport in the southwestern end of the Gulf of Lions (Northwestern Mediterranean)

Por A. Palanques, P. Puig, J. Guillén, X. Durrieu de Madron, M. Latasa, R. Scharek, J. Martin
Publicado em 2011-03-01

“... depth and in the northwestern Mediterranean basin at 2350-m depth. This paper is a synthesis of results...”
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33

Generic and Specific Adaptive Responses of Streptococcus pneumoniae to Challenge with Three Distinct Antimicrobial Peptides, Bacitracin, LL-37, and Nisin

Generic and Specific Adaptive Responses of Streptococcus pneumoniae to Challenge with Three Distinct Antimicrobial Peptides, Bacitracin, LL-37, and Nisin

Por Majchrzykiewicz, Joanna A., Kuipers, Oscar P., Bijlsma, Jetta J. E.
Publicado em 2010

“... proteins, i.e., putative ABC transporters, which can be used as targets for the development of new...”
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34

The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response

The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response

Por Roberts, Maxine J., Broome, Rebecca E., Kent, Toby C., Charlton, Steven J., Rosethorne, Elizabeth M.
Publicado no Respir Res (2018)

“...), and explore which can increase cAMP levels, and are most efficacious at inhibiting proliferation...”
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35

Safety and Feasibility of Soractelite Transperineal Focal Laser Ablation for Prostate Cancer and Short-term Quality of Life Analysis from a Multicenter Pilot Study

Safety and Feasibility of Soractelite Transperineal Focal Laser Ablation for Prostate Cancer and Short-term Quality of Life Analysis from a Multicenter Pilot Study

Por Luigi A.M.J.G. van Riel, Rob A.A. van Kollenburg, André N. Vis, Pim J. van Leeuwen, Theo M. de Reijke, Daniel M. de Bruin, Jorg R. Oddens
Publicado em 2022-05-01

“...: Focal treatment of localized prostate cancer can safely be performed in a daycare setting using a new...”
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36

A new strategy to amplify degraded RNA from small tissue samples for microarray studies

A new strategy to amplify degraded RNA from small tissue samples for microarray studies

Por Xiang, Charlie C., Chen, Mei, Ma, Li, Phan, Quang N., Inman, Jason M., Kozhich, Olga A., Brownstein, Michael J.
Publicado em 2003

“... with oligo(dT) with a T7 RNA polymerase promoter (T7dT) on the 5′ end, and subsequent transcriptions...”
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37

Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation

Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation

Por Wang, Zhiping, Dillon, Tara J., Pokala, Viji, Mishra, Snigdha, Labudda, Kirstin, Hunter, Brian, Stork, Philip J. S.
Publicado em 2006

“... of Rap1 by cyclic AMP (cAMP) can occur via cAMP-dependent protein kinase A (PKA)-independent and PKA...”
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38

Endogenously opsonized particles divert prostanoid action from lethal to protective in models of experimental endotoxemia.

Endogenously opsonized particles divert prostanoid action from lethal to protective in models of experimental endotoxemia.

Por Eierman, D F, Yagami, M, Erme, S M, Minchey, S R, Harmon, P A, Pratt, K J, Janoff, A S
Publicado em 1995

“... engagement events in defining the systemic prostaglandin response and offers a rationale for developing new...”
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39

Gene Expression and Transcription Factor Profiling Reveal Inhibition of Transcription Factor cAMP-response Element-binding Protein by γ-Herpesvirus Replication and Transcription Activator

Gene Expression and Transcription Factor Profiling Reveal Inhibition of Transcription Factor cAMP...

Por Brown, Helen J., Peng, Li, Harada, Josephine N., Walker, John R., Cole, Steven, Lin, Su-Fang, Zack, Jerome A., Chanda, Sumit K., Sun, Ren
Publicado em 2010

“...Herpesvirus replication involves the expression of over 80 viral genes in a well ordered sequence...”
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40

Effects of Assault Type on Cognitive Behaviour Therapy for Coexisting Depression and Alcohol Misuse

Effects of Assault Type on Cognitive Behaviour Therapy for Coexisting Depression and Alcohol Misuse

Por Kylie A. Bailey, Amanda L. Baker, Patrick McElduff, Mark A. Jones, Christopher Oldmeadow, David J. Kavanagh
Publicado em 2017-07-01

“.... Of the 278 DAISI participants, 220 consented to screening for past assault (either by a stranger or non...”
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