Resultados da pesquisa - (( drugs does develop them ) OR ((( drug doses devel ther ) OR ( drug dose devel ther ))))*

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Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

Por Park, Gab-jin, Bae, Soo Hyeon, Park, Wan-Su, Han, Seunghoon, Park, Min-Ho, Shin, Seok-Ho, Shin, Young G, Yim, Dong-Seok
Publicado no Drug Des Devel Ther (2017)

“...PURPOSE: A microdose drug–drug interaction (DDI) study may be a valuable tool for anticipating drug...”
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Evaluation of drug interactions between fimasartan and rosuvastatin after single and multiple doses in healthy Caucasians

Por Lee, Jieon, Rhee, Su-jin, Lee, SeungHwan, Yu, Kyung-Sang
Publicado no Drug Des Devel Ther (2018)

“... dose or as multiple doses to healthy Caucasians. METHODS: Thirty-six subjects were enrolled...”
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Predictive performance of gentamicin dosing nomograms

Por Lee, Jieon, Yoon, Seonghae, Shin, Donghoon, Han, HyeKyung, An, Hyungmi, Lee, Jongtae, Lim, Kyoung Soo, Yu, Kyung-Sang, Lee, Howard
Publicado em 2014

“... nomograms may be required in patients with IE, particularly for once-daily dosing. Therapeutic drug...”
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High-dose atorvastatin versus moderate dose on early vascular protection after ST-elevation myocardial infarction

Por Gavazzoni, Mara, Gorga, Elio, Derosa, Giuseppe, Maffioli, Pamela, Metra, Marco, Raddino, Riccardo
Publicado no Drug Des Devel Ther (2017)

“...BACKGROUND AND AIM: Clinical benefits of early high-dose statin therapy after acute coronary...”
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Dose-dependent effects of atorvastatin on myocardial infarction

Por Barbarash, Olga, Gruzdeva, Olga, Uchasova, Evgenya, Belik, Ekaterina, Dyleva, Yulia, Karetnikova, Victoria
Publicado no Drug Des Devel Ther (2015)

“...BACKGROUND: Dyslipidemia is a key factor determining the development of both myocardial infarction...”
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Dose proportionality and pharmacokinetics of carvedilol sustained-release formulation: a single dose-ascending 10-sequence incomplete block study

Por Kim, Yo Han, Choi, Hee Youn, Noh, Yook-Hwan, Lee, Shi Hyang, Lim, Hyeong-Seok, Kim, Chin, Bae, Kyun-Seop
Publicado no Drug Des Devel Ther (2015)

“... and high blood pressure. The aim of this study was to investigate the dose proportionality...”
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Is increasing the dose of Entecavir effective in partial virological responders?

Por Erturk, Ayse, Adnan Akdogan, Remzi, Parlak, Emine, Cure, Erkan, Cumhur Cure, Medine, Ozturk, Cinar
Publicado em 2014

“... transaminase (ALT) normalization at the end of 4 years. CONCLUSION: Increasing ETV dose from 0.5 mg to 1 mg...”
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Analysis of pramipexole dose–response relationships in Parkinson’s disease

Por Wang, Ying, Sun, Sheng-Gang, Zhu, Sui-Qiang, Liu, Chun-Feng, Liu, Yi-Ming, Di, Qing, Shang, Hui-Fang, Ren, Yan, Xiang, Wei, Chen, Sheng-Di
Publicado no Drug Des Devel Ther (2016)

“... for Parkinson’s disease (PD). A critical dose level above which a better benefit-to-harm ratio exists has not been...”
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Positives and negatives of nonsteroidal anti-inflammatory drugs in bone healing: the effects of these drugs on bone repair

Por Lisowska, Barbara, Kosson, Dariusz, Domaracka, Karolina
Publicado no Drug Des Devel Ther (2018)

“.... Nonsteroidal anti-inflammatory drugs (NSAIDs) play an essential role associated with their analgesic potency...”
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Application of physiologically based pharmacokinetic modeling in predicting drug–drug interactions for sarpogrelate hydrochloride in humans

Por Min, Jee Sun, Kim, Doyun, Park, Jung Bae, Heo, Hyunjin, Bae, Soo Hyeon, Seo, Jae Hong, Oh, Euichaul, Bae, Soo Kyung
Publicado no Drug Des Devel Ther (2016)

“...BACKGROUND: Evaluating the potential risk of metabolic drug–drug interactions (DDIs) is clinically...”
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Variability of the drug response to nonsteroidal anti-inflammatory drugs according to cyclooxygenase-2 genetic polymorphism

Por Lee, Sook Joung, Park, Min Kyu, Shin, Dong-Seong, Chun, Min Ho
Publicado no Drug Des Devel Ther (2017)

“... drugs (NSAIDs). We investigated the inhibitory effects on COX-2 after NSAIDs administration using a...”
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Population pharmacokinetics and dosing optimization of cefathiamidine in children with hematologic infection

Por Zhi, Li-Juan, Wang, Li, Chen, Xing-Kai, Zhai, Xiao-Ying, Wen, Li, Dong, Lei, Jacqz-Aigrain, Evelyne, Shi, Zhong-Ren, Zhao, Wei
Publicado no Drug Des Devel Ther (2018)

“... and Drug Administration for the treatment of infections caused by susceptible bacteria in both adults...”
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Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment

Por Halicki, Priscila C. B., Ferreira, Laís A., De Moura, Kelly C. G., Carneiro, Paula F., Del Rio, Karina P., Carvalho, Tatiane dos S. C., Pinto, Maria do C. F. R., da Silva, Pedro E. A., Ramos, Daniela F.
Publicado no Front Microbiol (2018)

“... of resistant Mycobacterium tuberculosis strains. These barriers reinforcing the need for development of new...”
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Paclitaxel: new uses for an old drug

Por Zhang, Dongshan, Yang, Ruhao, Wang, Shixuan, Dong, Zheng
Publicado em 2014

“...Paclitaxel (Taxol), one of the most important anticancer drugs, has been used for therapy...”
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A once-daily dose of tadalafil for erectile dysfunction: compliance and efficacy

Por Washington, Samuel L, Shindel, Alan W
Publicado em 2010

“... of once-daily dose of tadalafil by the US Food and Drug Administration for the management of ED...”
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Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Por Kim, Yo Han, Choi, Hee Youn, Lim, Hyeong-Seok, Lee, Shi Hyang, Jeon, Hae Sun, Hong, Donghyun, Kim, Seong Su, Choi, Young Kweon, Bae, Kyun-Seop
Publicado no Drug Des Devel Ther (2015)

“.... The aim of this randomized, single-blind, placebo-controlled, single-dose, dose-escalation study...”
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Outcome of stroke patients receiving different doses of recombinant tissue plasminogen activator

Por Ong, Cheung-Ter, Wong, Yi-Sin, Wu, Chi-Shun, Su, Yu-Hsiang
Publicado no Drug Des Devel Ther (2017)

“...BACKGROUND AND PURPOSE: Intravenous recombinant tissue plasminogen activator (tPA) at a dose of 0.9...”
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Dose-proportional pharmacokinetic properties of GLA5PR GLARS-NF1 controlled-release pregabalin...

Por Shin, Kwang-Hee, Jeon, Ji-Young, Jang, Kyungho, Kim, Tae-Eun, Kim, Min-Gul
Publicado no Drug Des Devel Ther (2018)

“...PURPOSE: The aim of this study was to evaluate the dose-proportional pharmacokinetic...”
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Efficacy and safety of different doses of a slow release corticosteroid implant for macular edema

Por Hall, John
Publicado no Drug Des Devel Ther (2016)

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Spotlight on valsartan–sacubitril fixed-dose combination for heart failure: the evidence to date

Por Vilela-Martin, José Fernando
Publicado no Drug Des Devel Ther (2016)

“.... This review highlights the main pharmacological developments in the field of heart failure with reduced...”
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