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1

In vitro cytotoxicity of two novel oral formulations of Amphotericin B (iCo-009 and iCo-010) against Candida albicans, human monocytic and kidney cell lines

In vitro cytotoxicity of two novel oral formulations of Amphotericin B (iCo-009 and iCo-010) against Candida albicans, human monocytic and kidney cell lines

Por Leon, Carlos G, Lee, Jinkyung, Bartlett, Karen, Gershkovich, Pavel, Wasan, Ellen K, Zhao, Jinying, Clement, John G, Wasan, Kishor M
Publicado em 2011

“...-009 and iCo-010) against Candida albicans, human kidney (293T) cells and monocytic (THP1) cells...”
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2

Pediatric Lupus – Are There Differences in Presentation, Genetics, Response to Therapy, Damage Accrual Compared to Adult Lupus?

Pediatric Lupus – Are There Differences in Presentation, Genetics, Response to Therapy, Damage Accrual Compared to Adult Lupus?

Por Mina, Rina, Brunner, Hermine I
Publicado em 2010

“...Some complement deficiencies predispose to SLE early in life. Currently, there are no known unique...”
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3

Potential of chromatin modifying compounds for the treatment of Alzheimer's disease

Potential of chromatin modifying compounds for the treatment of Alzheimer's disease

Por Karagiannis, Tom C., Ververis, Katherine
Publicado em 2012

“... and sirtuin 1 activator resveratrol has been shown to have beneficial effects in animal models of disease...”
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4

Development of Levofloxacin inhalation solution to treat Pseudomonas aeruginosa in patients with cystic fibrosis

Development of Levofloxacin inhalation solution to treat Pseudomonas aeruginosa in patients with cystic fibrosis

Por Stockmann, Chris, Sherwin, Catherine M.T., Ampofo, Krow, Spigarelli, Michael G.
Publicado no Ther Adv Respir Dis (2013)

“... levofloxacin solution (MP-376) is a novel therapy that is currently being evaluated in phase I, II, and III...”
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5

New agents for the treatment of hepatitis C in patients co-infected with HIV

New agents for the treatment of hepatitis C in patients co-infected with HIV

Por Munteanu, Daniela I., Rockstroh, Jürgen K.
Publicado em 2013

“...) protease inhibitors (PIs), boceprevir (BOC) and telaprevir (TVR), for the treatment of genotype 1 infection...”
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6

Suppression of chikungunya virus replication and differential innate responses of human peripheral blood mononuclear cells during co-infection with dengue virus

Suppression of chikungunya virus replication and differential innate responses of human peripheral blood mononuclear cells during co-infection with dengue virus

Por Ruiz Silva, Mariana, Aguilar Briseño, José A., Upasani, Vinit, van der Ende-Metselaar, Heidi, Smit, Jolanda M., Rodenhuis-Zybert, Izabela A.
Publicado no PLoS Negl Trop Dis (2017)

“... has led to an upsurge in reported cases of DENV/CHIKV co-infections. Unfortunately, at present we have...”
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7

HIV-1 transmitted drug resistance-associated mutations and mutation co-variation in HIV-1 treatment-naïve MSM from 2011 to 2013 in Beijing, China

HIV-1 transmitted drug resistance-associated mutations and mutation co-variation in HIV-1 treatment-naïve MSM from 2011 to 2013 in Beijing, China

Por Jiao, Yang, Li, Shuming, Li, Zhenpeng, Zhang, Zheng, Zhao, Jianhong, Li, Li, Wang, Lijuan, Yin, Qianqian, Wang, Yan, Zeng, Zhaoli, Shao, Yiming, Ma, Liying
Publicado no BMC Infect Dis (2014)

“... samples had at least one TDR-associated mutation, mainly including L10I/V (6.3%), A71L/T/V (6.3%), V179D/E...”
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8

The geographic distribution patterns of HIV-, HCV- and co-infections among drug users in a national methadone maintenance treatment program in Southwest China

The geographic distribution patterns of HIV-, HCV- and co-infections among drug users in a national methadone maintenance treatment program in Southwest China

Por Zhou, Yi-Biao, Liang, Song, Wang, Qi-Xing, Gong, Yu-Han, Nie, Shi-Jiao, Nan, Lei, Yang, Ai-Hui, Liao, Qiang, Song, Xiu-Xia, Jiang, Qing-Wu
Publicado em 2014

“...BACKGROUND: HIV-, HCV- and HIV/HCV co-infections among drug users have become a rapidly emerging...”
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9

Impact of HMG-CoA reductase inhibitors on the incidence of polyomavirus-associated nephropathy in renal transplant recipients with human BK polyomavirus viremia

Impact of HMG-CoA reductase inhibitors on the incidence of polyomavirus-associated nephropathy...

Por Gabardi, S., Ramasamy, S., Kim, M., Klasek, R., Carter, D., Mackenzie, M.R., Chandraker, A., Tan, C.S.
Publicado no Transpl Infect Dis (2015)

“... with documented BKPyV viremia (viral load >500 copies/mL on 2 consecutive tests) were included. Group I consisted...”
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10

Population Genetics of the Filarial Worm Wuchereria bancrofti in a Post-treatment Region of Papua New Guinea: Insights into Diversity and Life History

Population Genetics of the Filarial Worm Wuchereria bancrofti in a Post-treatment Region of Papua New Guinea: Insights into Diversity and Life History

Por Small, Scott T., Ramesh, Akshaya, Bun, Krufinta, Reimer, Lisa, Thomsen, Edward, Baea, Manasseh, Bockarie, Moses J., Siba, Peter, Kazura, James W., Tisch, Daniel J., Zimmerman, Peter A.
Publicado em 2013

“... Oxidase 1 (CO1) gene from 16 people infected with Wb. Patients were selected from 7 villages encompassing...”
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11

Pathology is a critical aspect of preclinical aging studies

Pathology is a critical aspect of preclinical aging studies

Por Ladiges, Warren, Ikeno, Yuji, Liggitt, Denny, Treuting, Piper M.
Publicado em 2013

“... challenge is including it in aging studies because there is currently a lack of specialized expertise...”
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12

Isolation of bifidobacteria for blood group secretor status targeted personalised nutrition

Isolation of bifidobacteria for blood group secretor status targeted personalised nutrition

Por Mäkivuokko, Harri, Wacklin, Pirjo, Koenen, Marjorie E., Laamanen, Karoliina, Alakulppi, Noora, Venema, Koen, Mättö, Jaana
Publicado em 2012

“...BACKGROUND: Currently, there is a constant need to find microbial products for maintaining or even...”
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13

Effects of yoga training in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis

Effects of yoga training in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis

Por Liu, Xun-Chao, Pan, Lei, Hu, Qing, Dong, Wei-Ping, Yan, Jun-Hong, Dong, Liang
Publicado em 2014

“...INTRODUCTION: Currently, several studies have assessed the effect of yoga training...”
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14

An evolutionary approach to optimizing glucose-6-phosphatase-α enzymatic activity for gene therapy of glycogen storage disease type Ia

An evolutionary approach to optimizing glucose-6-phosphatase-α enzymatic activity for gene therapy of glycogen storage disease type Ia

Por Zhang, Lisa, Cho, Jun-Ho, Arnaoutova, Irina, Mansfield, Brian C., Chou, Janice Y.
Publicado no J Inherit Metab Dis (2019)

“..., following a short fast. We have shown that G6pc-deficient (G6pc−/−) mice treated with recombinant adeno...”
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15

Evaluation of the efficacy of a new insomnia service providing cognitive behavioural therapy for insomnia

Evaluation of the efficacy of a new insomnia service providing cognitive behavioural therapy for insomnia

Por Berger, Louise
Publicado no J Thorac Dis (2016)

“... programme, providing one to one Cognitive Behavioural Therapy for Insomnia (CBT-I) was introduced...”
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16

Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways

Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways

Por Bruzzese, F, Pucci, B, Milone, M R, Ciardiello, C, Franco, R, Chianese, M I, Rocco, M, Di Gennaro, E, Leone, A, Luciano, A, Arra, C, Santini, D, Caraglia, M, Budillon, A
Publicado em 2013

“... in a PCa xenograft model. The co-administration of the antioxidant N-acetyl-L-cysteine blocked...”
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17

Hyperactivity and attention deficits in mice with decreased levels of stress-inducible phosphoprotein 1 (STIP1)

Hyperactivity and attention deficits in mice with decreased levels of stress-inducible phosphoprotein 1 (STIP1)

Por Beraldo, Flavio H., Thomas, Anu, Kolisnyk, Benjamin, Hirata, Pedro H., De Jaeger, Xavier, Martyn, Amanda C., Fan, Jue, Goncalves, Daniela F., Cowan, Matthew F., Masood, Talal, Martins, Vilma R., Gros, Robert, Prado, Vania F., Prado, Marco A. M.
Publicado no Dis Model Mech (2015)

“...Stress-inducible phosphoprotein I (STIP1, STI1 or HOP) is a co-chaperone intermediating Hsp70/Hsp90...”
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18

Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function

Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function

Por Felzen, V, Hiebel, C, Koziollek-Drechsler, I, Reißig, S, Wolfrum, U, Kögel, D, Brandts, C, Behl, C, Morawe, T
Publicado no Cell Death Dis (2015)

“...-positive tumors are currently treated with anti-hormone therapy to inhibit ER signaling. It is well known...”
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19

Development of a glycoconjugate vaccine to prevent invasive Salmonella Typhimurium infections in sub-Saharan Africa

Development of a glycoconjugate vaccine to prevent invasive Salmonella Typhimurium infections in sub-Saharan Africa

Por Baliban, Scott M., Yang, Mingjun, Ramachandran, Girish, Curtis, Brittany, Shridhar, Surekha, Laufer, Rachel S., Wang, Jin Y., Van Druff, John, Higginson, Ellen E., Hegerle, Nicolas, Varney, Kristen M., Galen, James E., Tennant, Sharon M., Lees, Andrew, MacKerell, Alexander D., Levine, Myron M., Simon, Raphael
Publicado no PLoS Negl Trop Dis (2017)

“...), Typhimurium (STm) and monophasic variant 1,4,[5],12:i:- are a major health problem in infants and young...”
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20

The interaction between artemether-lumefantrine and lopinavir/ritonavir-based antiretroviral therapy in HIV-1 infected patients

The interaction between artemether-lumefantrine and lopinavir/ritonavir-based antiretroviral therapy in HIV-1 infected patients

Por Kredo, T., Mauff, K., Workman, L., Van der Walt, J. S., Wiesner, L., Smith, P. J., Maartens, G., Cohen, K., Barnes, K. I.
Publicado no BMC Infect Dis (2016)

“...BACKGROUND: Artemether-lumefantrine is currently the most widely recommended treatment...”
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