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1

Neutrophil-Associated Central Nervous System Inflammation in Tuberculous Meningitis Immune Reconstitution Inflammatory Syndrome

Neutrophil-Associated Central Nervous System Inflammation in Tuberculous Meningitis Immune Reconstitution Inflammatory Syndrome

Por Marais, Suzaan, Wilkinson, Katalin A., Lesosky, Maia, Coussens, Anna K., Deffur, Armin, Pepper, Dominique J., Schutz, Charlotte, Ismail, Zahiera, Meintjes, Graeme, Wilkinson, Robert J.
Publicado no Clin Infect Dis (2014)

“... S100A8/A9, are closely associated with the central nervous system inflammation that characterizes TBM...”
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2

Modeling cytokine regulatory network dynamics driving neuroinflammation in central nervous system disorders

Modeling cytokine regulatory network dynamics driving neuroinflammation in central nervous system disorders

Por Anderson, Warren D., Vadigepalli, Rajanikanth
Publicado no Drug Discov Today Dis Models (2017)

“...A central goal of pharmacological efforts to treat central nervous system (CNS) diseases...”
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3

Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind

Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind

Por Hsieh, Jenny, Eisch, Amelia J.
Publicado em 2010

“...In mature, differentiated neurons in the central nervous system (CNS), epigenetic mechanisms...”
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4

The role of adipose triglyceride lipase in lipid and glucose homeostasis: lessons from transgenic mice

The role of adipose triglyceride lipase in lipid and glucose homeostasis: lessons from transgenic mice

Por Trites, Michael J., Clugston, Robin D.
Publicado no Lipids Health Dis (2019)

“...The ability of mammals to store and draw on fat reserves has been a driving force throughout...”
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5

MECHANISMS OF APNEA

MECHANISMS OF APNEA

Por Eckert, Danny J., Malhotra, Atul, Jordan, Amy S.
Publicado em 2009

“... by repetitive narrowing or collapse of the pharyngeal airway during sleep. Conversely, central sleep apnea (CSA...”
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6

Drosophila tools and assays for the study of human diseases

Drosophila tools and assays for the study of human diseases

Por Ugur, Berrak, Chen, Kuchuan, Bellen, Hugo J.
Publicado no Dis Model Mech (2016)

“... of specific genes in the central nervous system, heart, liver and kidney, and provide examples of the use...”
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7

Cell cycle inhibition as a strategy for treatment of central nervous system diseases which must not block normal neurogenesis

Cell cycle inhibition as a strategy for treatment of central nervous system diseases which must not block normal neurogenesis

Por Liu, Da-Zhi, Ander, Bradley P., Sharp, Frank R.
Publicado em 2009

“...Classically, the cell cycle is regarded as the central process leading to cellular proliferation...”
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8

Toll-like Receptor 4 Signaling on Dendritic Cells Suppresses Polymorphonuclear Leukocyte CXCR2 Expression and Trafficking via Interleukin 10 During Intra-abdominal Sepsis

Toll-like Receptor 4 Signaling on Dendritic Cells Suppresses Polymorphonuclear Leukocyte CXCR2 Expression and Trafficking via Interleukin 10 During Intra-abdominal Sepsis

Por Deng, Meihong, Ma, Tao, Yan, Zhengzheng, Zettel, Kent R., Scott, Melanie J., Liao, Hong, Frank, Alicia, Morelli, Adrian E., Sodhi, Chhinder P., Hackam, David J., Billiar, Timothy R.
Publicado no J Infect Dis (2016)

“... (DCs) are known to play a central role in microbial detection, alerting the immune system...”
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9

Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation

Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain...

Por Schultz, Laura E., Haltom, Jeffrey A., Almeida, Maira P., Wierson, Wesley A., Solin, Staci L., Weiss, Trevor J., Helmer, Jordan A., Sandquist, Elizabeth J., Shive, Heather R., McGrail, Maura
Publicado no Dis Model Mech (2018)

“... regulators driving oncogenesis in a zebrafish retinoblastoma 1 (rb1) somatic-targeting model of RB1 mutant...”
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10

Afferent neural pathways mediating cough in animals and humans

Afferent neural pathways mediating cough in animals and humans

Por Narula, Monica, McGovern, Alice E., Yang, Seung-Kwon, Farrell, Michael J., Mazzone, Stuart B.
Publicado no J Thorac Dis (2014)

“... system and drive reflex changes in respiratory and airway functions. But less appreciated...”
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11

The neuropsychological phenotype of Chediak-Higashi disease

The neuropsychological phenotype of Chediak-Higashi disease

Por Shirazi, Talia N., Snow, Joseph, Ham, Lillian, Raglan, Greta B., Wiggs, Edythe A., Summers, Angela C., Toro, Camilo, Introne, Wendy J.
Publicado no Orphanet J Rare Dis (2019)

“... accommodations. The source of cognitive deficits is probably multifactorial including central nervous system...”
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12

Direct and indirect costs and cost-driving factors of Tuberous sclerosis complex in children, adolescents, and caregivers: a multicenter cohort study

Direct and indirect costs and cost-driving factors of Tuberous sclerosis complex in children, adolescents, and caregivers: a multicenter cohort study

Por Grau, Janina, Zöllner, Johann Philipp, Schubert-Bast, Susanne, Kurlemann, Gerhard, Hertzberg, Christoph, Wiemer-Kruel, Adelheid, Bast, Thomas, Bertsche, Astrid, Bettendorf, Ulrich, Fiedler, Barbara, Hahn, Andreas, Hartmann, Hans, Hornemann, Frauke, Immisch, Ilka, Jacobs, Julia, Kieslich, Matthias, Klein, Karl Martin, Klotz, Kerstin A., Kluger, Gerhard, Knuf, Markus, Mayer, Thomas, Marquard, Klaus, Meyer, Sascha, Muhle, Hiltrud, Müller-Schlüter, Karen, Noda, Anna H., Ruf, Susanne, Sauter, Matthias, Schlump, Jan-Ulrich, Syrbe, Steffen, Thiels, Charlotte, Trollmann, Regina, Wilken, Bernd, Willems, Laurent M., Rosenow, Felix, Strzelczyk, Adam
Publicado no Orphanet J Rare Dis (2021)

“... and systems, characterized by benign growths. This German multicenter study estimated the disease-specific...”
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13

Direct and indirect costs and cost-driving factors in adults with tuberous sclerosis complex: a multicenter cohort study and a review of the literature

Direct and indirect costs and cost-driving factors in adults with tuberous sclerosis complex: a multicenter cohort study and a review of the literature

Por Zöllner, Johann Philipp, Grau, Janina, Rosenow, Felix, Sauter, Matthias, Knuf, Markus, Kurlemann, Gerhard, Mayer, Thomas, Hertzberg, Christoph, Bertsche, Astrid, Immisch, Ilka, Klein, Karl Martin, Knake, Susanne, Marquard, Klaus, Meyer, Sascha, Noda, Anna H., von Podewils, Felix, Schäfer, Hannah, Thiels, Charlotte, Willems, Laurent M., Zukunft, Bianca, Schubert-Bast, Susanne, Strzelczyk, Adam
Publicado no Orphanet J Rare Dis (2021)

“... by benign growths due to TSC1 or TSC2 mutations. This German multicenter study estimated the costs...”
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14

8th European Conference on Rare Diseases & Orphan Products (ECRD 2016): Edinburgh, UK. 26-28 May 2016

8th European Conference on Rare Diseases & Orphan Products (ECRD 2016): Edinburgh, UK. 26-28 May 2016

Por Schlander, Michael, Holm, Søren, Nord, Erik, Richardson, Jeff, Garattini, Silvio, Kolominsky-Rabas, Peter, Marshall, Deborah, Persson, Ulf, Postma, Maarten, Simoens, Steven, de Solà Morales, Oriol, Tolley, Keith, Toumi, Mondher, Telser, Harry, Bonham, James R, Hintner, Helmut, Diem, Anja, Laimer, Martin, Hébert, Réjean, Dasgupta, Nabarun, Pierce, Carrie E., Jordan, Melissa, Bori, Barbara, Fors, Mohanad, Prazakova, Emilie, Day, Simon, Croce, Thomas J., Fransson, Jonas, Wood, Philip, Lauridsen, Anne-Grethe, Higgs, Joanne, Aleksovska, Vesna Stojmirova, Olsen, Christina, Head, Ritchie, Asero, Antonio, Papa, Vincenzo, van Kan, Christa, Favennec, Loic, Venturella, Silvana, Salvador, Michela, Krol, Alan, Nielsen, Stephanie J., Holm, Birthe B., Lewi, Daniel, Durão, Patricia, Band, Heather, West, Andrea, Hammann, Marinda J. A., Effing-Boele, Marije C., Dekker, Hanka K., Hunter, Amy, Simpson, Amy, Liu, Gumei, Needleman, Katherine, Lewis, Debra, Rao, Gayatri, Simpson, Amy, Hunter, Amy, Whitaker, Martin J., Castro, Raquel
Publicado no Orphanet J Rare Dis (2016)

“... diseases to manage the social – and healthcare systems Stephanie J. Nielsen, Birthe B. Holm P6 The eAcademy...”
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15

SLC9A3/NHE3 dysregulation and dilated intercellular spaces in eosinophilic esophagitis

SLC9A3/NHE3 dysregulation and dilated intercellular spaces in eosinophilic esophagitis

Por Zeng, Chang, Vanoni, Simone, Wu, David, Caldwell, Julie M., Wheeler, Justin C., Arora, Kavisha, Noah, Taeko K., Waggoner, Lisa, Besse, John A., Yamani, Amnah N., Uddin, Jazib, Rochman, Mark, Wen, Ting, Chehade, Mirna, Collins, Margaret, Mukkada, Vincent, Putnam, Philip, Naren, Anjaparavanda P., Rothenberg, Marc E., Hogan, Simon P.
Publicado no J Allergy Clin Immunol (2018)

“... intercellular spaces (DIS). The underlying molecular processes that drive the histopathologic features of EoE...”
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16

Quality Improvement Through the Introduction of Interdisciplinary Geriatric Hemodialysis Rehabilitation Care

Quality Improvement Through the Introduction of Interdisciplinary Geriatric Hemodialysis Rehabilitation Care

Por Li, Marilyn, Porter, Eveline, Lam, Robert, Jassal, Sarbjit V.
Publicado no Am J Kidney Dis (2007)

“... to their home. Am J Kidney Dis 00:00-00...”
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17

Insulin expressing hepatocytes not destroyed in transgenic NOD mice

Insulin expressing hepatocytes not destroyed in transgenic NOD mice

Por Tabiin, Muhammad T, White, Christopher P, Morahan, Grant, Tuch, Bernard E
Publicado em 2004

“...BACKGROUND: The liver has been suggested as a suitable target organ for gene therapy of Type 1...”
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18

543. An Integrated Safety Analysis Comparing Once-Daily Doravirine (DOR) to Darunavir+Ritonavir (DRV+r) and Efavirenz (EFV) in HIV-1-Infected, Antiretroviral Therapy (ART)-Naïve Adults

543. An Integrated Safety Analysis Comparing Once-Daily Doravirine (DOR) to Darunavir+Ritonavir (DRV+r) and Efavirenz (EFV) in HIV-1-Infected, Antiretroviral Therapy (ART)-Naïve Adults

Por Thompson, Melanie, Orkin, Chloe, Molina, Jean-Michel, Gatell, Jose, Sax, Paul, Cahn, Pedro, Squires, Kathleen, Zhou, Yan, Xu, Xia, Rodgers, Anthony, Kumar, Sushma, Teppler, Hedy, Martin, Elizabeth, Hanna, George, Hwang, Carey
Publicado no Open Forum Infect Dis (2018)

“...007 and DRIVE-AHEAD for treatment of HIV-1 in ART-naïve adults. The NRTI background included FTC/TDF...”
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19

Retinopathy-Positive Cerebral Malaria Is Associated With Greater Inflammation, Blood-Brain Barrier Breakdown, and Neuronal Damage Than Retinopathy-Negative Cerebral Malaria

Retinopathy-Positive Cerebral Malaria Is Associated With Greater Inflammation, Blood-Brain Barrier Breakdown, and Neuronal Damage Than Retinopathy-Negative Cerebral Malaria

Por Villaverde, Chandler, Namazzi, Ruth, Shabani, Estela, Park, Gregory S, Datta, Dibyadyuti, Hanisch, Benjamin, Opoka, Robert O, John, Chandy C
Publicado no J Pediatric Infect Dis Soc (2019)

“..., we assessed the pathophysiology of RP and RN CM. METHODS: We compared markers of systemic and central...”
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20

Hedonic Homeostatic Dysregulation as a Driver of Drug-Seeking Behavior

Hedonic Homeostatic Dysregulation as a Driver of Drug-Seeking Behavior

Por Koob, George F.
Publicado em 2008

“... intake, and the excessive drug taking derives from multiple motivational mechanisms. One such mechanism...”
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