Resultados da pesquisa - ((((((drug dna) OR (drug code))) OR (((drug dose) OR (drug doses))))) OR (drug deal)) devel ther

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1

Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

Por Park, Gab-jin, Bae, Soo Hyeon, Park, Wan-Su, Han, Seunghoon, Park, Min-Ho, Shin, Seok-Ho, Shin, Young G, Yim, Dong-Seok
Publicado no Drug Des Devel Ther (2017)

“...PURPOSE: A microdose drug–drug interaction (DDI) study may be a valuable tool for anticipating drug...”
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2

Predictive performance of gentamicin dosing nomograms

Predictive performance of gentamicin dosing nomograms

Por Lee, Jieon, Yoon, Seonghae, Shin, Donghoon, Han, HyeKyung, An, Hyungmi, Lee, Jongtae, Lim, Kyoung Soo, Yu, Kyung-Sang, Lee, Howard
Publicado em 2014

“... nomograms may be required in patients with IE, particularly for once-daily dosing. Therapeutic drug...”
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3

High-dose atorvastatin versus moderate dose on early vascular protection after ST-elevation myocardial infarction

High-dose atorvastatin versus moderate dose on early vascular protection after ST-elevation myocardial infarction

Por Gavazzoni, Mara, Gorga, Elio, Derosa, Giuseppe, Maffioli, Pamela, Metra, Marco, Raddino, Riccardo
Publicado no Drug Des Devel Ther (2017)

“...BACKGROUND AND AIM: Clinical benefits of early high-dose statin therapy after acute coronary...”
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4

Dose-dependent effects of atorvastatin on myocardial infarction

Dose-dependent effects of atorvastatin on myocardial infarction

Por Barbarash, Olga, Gruzdeva, Olga, Uchasova, Evgenya, Belik, Ekaterina, Dyleva, Yulia, Karetnikova, Victoria
Publicado no Drug Des Devel Ther (2015)

“..., resulted in a decrease in free fatty acid levels. The positive effect of low-dose atorvastatin (20 mg/day...”
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5

Dose proportionality and pharmacokinetics of carvedilol sustained-release formulation: a single dose-ascending 10-sequence incomplete block study

Dose proportionality and pharmacokinetics of carvedilol sustained-release formulation: a single dose-ascending 10-sequence incomplete block study

Por Kim, Yo Han, Choi, Hee Youn, Noh, Yook-Hwan, Lee, Shi Hyang, Lim, Hyeong-Seok, Kim, Chin, Bae, Kyun-Seop
Publicado no Drug Des Devel Ther (2015)

“... and high blood pressure. The aim of this study was to investigate the dose proportionality...”
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6

Is increasing the dose of Entecavir effective in partial virological responders?

Is increasing the dose of Entecavir effective in partial virological responders?

Por Erturk, Ayse, Adnan Akdogan, Remzi, Parlak, Emine, Cure, Erkan, Cumhur Cure, Medine, Ozturk, Cinar
Publicado em 2014

“... of the treatment, those with detectable hepatitis B virus (HBV-DNA) were randomized to either ETV 0.5 mg or 1 mg...”
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7

Analysis of pramipexole dose–response relationships in Parkinson’s disease

Analysis of pramipexole dose–response relationships in Parkinson’s disease

Por Wang, Ying, Sun, Sheng-Gang, Zhu, Sui-Qiang, Liu, Chun-Feng, Liu, Yi-Ming, Di, Qing, Shang, Hui-Fang, Ren, Yan, Xiang, Wei, Chen, Sheng-Di
Publicado no Drug Des Devel Ther (2016)

“... for Parkinson’s disease (PD). A critical dose level above which a better benefit-to-harm ratio exists has not been...”
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8

Application of physiologically based pharmacokinetic modeling in predicting drug–drug interactions for sarpogrelate hydrochloride in humans

Application of physiologically based pharmacokinetic modeling in predicting drug–drug interactions for sarpogrelate hydrochloride in humans

Por Min, Jee Sun, Kim, Doyun, Park, Jung Bae, Heo, Hyunjin, Bae, Soo Hyeon, Seo, Jae Hong, Oh, Euichaul, Bae, Soo Kyung
Publicado no Drug Des Devel Ther (2016)

“...BACKGROUND: Evaluating the potential risk of metabolic drug–drug interactions (DDIs) is clinically...”
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9

Variability of the drug response to nonsteroidal anti-inflammatory drugs according to cyclooxygenase-2 genetic polymorphism

Variability of the drug response to nonsteroidal anti-inflammatory drugs according to cyclooxygenase-2 genetic polymorphism

Por Lee, Sook Joung, Park, Min Kyu, Shin, Dong-Seong, Chun, Min Ho
Publicado no Drug Des Devel Ther (2017)

“... drugs (NSAIDs). We investigated the inhibitory effects on COX-2 after NSAIDs administration using a...”
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10

Paclitaxel: new uses for an old drug

Paclitaxel: new uses for an old drug

Por Zhang, Dongshan, Yang, Ruhao, Wang, Shixuan, Dong, Zheng
Publicado em 2014

“...Paclitaxel (Taxol), one of the most important anticancer drugs, has been used for therapy...”
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11

A once-daily dose of tadalafil for erectile dysfunction: compliance and efficacy

A once-daily dose of tadalafil for erectile dysfunction: compliance and efficacy

Por Washington, Samuel L, Shindel, Alan W
Publicado em 2010

“... of once-daily dose of tadalafil by the US Food and Drug Administration for the management of ED...”
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12

Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Por Kim, Yo Han, Choi, Hee Youn, Lim, Hyeong-Seok, Lee, Shi Hyang, Jeon, Hae Sun, Hong, Donghyun, Kim, Seong Su, Choi, Young Kweon, Bae, Kyun-Seop
Publicado no Drug Des Devel Ther (2015)

“.... The aim of this randomized, single-blind, placebo-controlled, single-dose, dose-escalation study...”
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13

Outcome of stroke patients receiving different doses of recombinant tissue plasminogen activator

Outcome of stroke patients receiving different doses of recombinant tissue plasminogen activator

Por Ong, Cheung-Ter, Wong, Yi-Sin, Wu, Chi-Shun, Su, Yu-Hsiang
Publicado no Drug Des Devel Ther (2017)

“...BACKGROUND AND PURPOSE: Intravenous recombinant tissue plasminogen activator (tPA) at a dose of 0.9...”
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14

High-dose dexamethasone induced LPS-stimulated rat alveolar macrophages apoptosis

High-dose dexamethasone induced LPS-stimulated rat alveolar macrophages apoptosis

Por Zeng, Si, Qiao, Hui, Lv, Xue-wen, Fan, Dan, Liu, Tong, Xie, Dongli
Publicado no Drug Des Devel Ther (2017)

“...Prolonged administration of an excessive dose of corticosteroids proved to be harmful for patients...”
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15

Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO(®) (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers

Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination...

Por Choi, YoonJung, Han, HyeKyung, Shin, Dongseong, Lim, Kyoung Soo, Yu, Kyung-Sang
Publicado no Drug Des Devel Ther (2015)

“... and esomeprazole after a single oral dose. Both drugs were well-tolerated without any safety issues....”
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16

Spotlight on valsartan–sacubitril fixed-dose combination for heart failure: the evidence to date

Spotlight on valsartan–sacubitril fixed-dose combination for heart failure: the evidence to date

Por Vilela-Martin, José Fernando
Publicado no Drug Des Devel Ther (2016)

“... ejection fraction, giving emphasis to a drug that has a dual-acting inhibition of the neprilysin and renin...”
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17

Single dose pharmacokinetic equivalence study of two gabapentin preparations in healthy subjects

Single dose pharmacokinetic equivalence study of two gabapentin preparations in healthy subjects

Por Tjandrawinata, Raymond R, Setiawati, Effi, Putri, Ratih Sofia Ika, Yunaidi, Danang Agung, Amalia, Fawzia, Susanto, Liana W
Publicado em 2014

“... of the test drug or of the reference drug. Blood samples were drawn immediately before taking the drug...”
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18

Aclidinium bromide/formoterol fixed-dose combination therapy for COPD: the evidence to date

Aclidinium bromide/formoterol fixed-dose combination therapy for COPD: the evidence to date

Por Moitra, Subhabrata, Bhome, Arvind B, Brashier, Bill B
Publicado no Drug Des Devel Ther (2015)

“..., given the rising morbidity and mortality due to this disease. The fixed-dose combination of aclidinium...”
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19

Efficacy and safety of different doses of a slow release corticosteroid implant for macular edema

Efficacy and safety of different doses of a slow release corticosteroid implant for macular edema

Por Hall, John
Publicado no Drug Des Devel Ther (2016)

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20

Safety and pharmacokinetics of dicloxacillin in healthy Chinese volunteers following single and multiple oral doses

Safety and pharmacokinetics of dicloxacillin in healthy Chinese volunteers following single and multiple oral doses

Por Wu, Guolan, Zheng, Yunliang, Zhou, Huili, Hu, Xingjiang, Liu, Jian, Zhai, You, Zhu, Meixiang, Wu, Lihua, Shentu, Jianzhong
Publicado no Drug Des Devel Ther (2015)

“... oral dose of 0.25–2.0 g dicloxacillin sodium, the maximum plasma drug concentration (C(max...”
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