Spatially resolved transcriptomics provide a new method for cancer research

Por Bowen Zheng, Lin Fang
Publicado em 2022-05-01

The DNA/RNA helicase DHX9 contributes to the transcriptional program of the androgen receptor in prostate cancer

Por Lidia Chellini, Marco Pieraccioli, Claudio Sette, Maria Paola Paronetto
Publicado em 2022-05-01

Retraction Note: TRIM29 facilitates the epithelial‑to-mesenchymal transition and the progression of colorectal cancer via the activation of the Wnt/β-catenin signaling pathway

Por Juntao Sun, Tianyu Zhang, Mengmeng Cheng, Liwen Hong, Chen Zhang, Mengfan Xie, Peijun Sun, Rong Fan, Zhengting Wang, Lei Wang, Jie Zhong
Publicado em 2022-05-01

Correction: GPR119 agonist enhances gefitinib responsiveness through lactate-mediatedinhibition of autophagy

Por Ji Hye Im, Keon Wook Kang, Sun Young Kim, Yoon Gyoon Kim, Yong Jin An, Sunghyouk Park, Byung Hwa Jung, Song-Yi Choi, Jin-Sun Lee, Keon Wook Kang
Publicado em 2022-05-01

TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway in bladder cancer

Por Ming Chi, Jiao Liu, Chenxue Mei, Yaxing Shi, Nanqi Liu, Xuefeng Jiang, Chang Liu, Nan Xue, Hong Hong, Jisheng Xie, Xun Sun, Bo Yin, Xin Meng, Biao Wang
Publicado em 2022-05-01

A positive feedback loop between gastric cancer cells and tumor-associated macrophage induces malignancy progression

Por Haiyan Piao, Lingfeng Fu, Yuxin Wang, Yang Liu, Yue Wang, Xiangyu Meng, Dong Yang, Xiang Xiao, Jun Zhang
Publicado em 2022-05-01

A novel protein encoded by ZCRB1-induced circHEATR5B suppresses aerobic glycolysis of GBM through phosphorylation of JMJD5

Por Jian Song, Jian Zheng, Xiaobai Liu, Weiwei Dong, Chunqing Yang, Di Wang, Xuelei Ruan, Yubo Zhao, Libo Liu, Ping Wang, Mengyang Zhang, Yunhui Liu
Publicado em 2022-05-01

FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma

Por Qingfeng Shang, Haizhen Du, Xiaowen Wu, Qian Guo, Fenghao Zhang, Ziqi Gong, Tao Jiao, Jun Guo, Yan Kong
Publicado em 2022-05-01

GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma

Por Zhiqing Fang, Ning Zhang, Xiaotian Yuan, Xiangling Xing, Xiaofeng Li, Xin Qin, Zhengfang Liu, Shiyong Neo, Cheng Liu, Feng Kong, Magnus Björkholm, Yidong Fan, Dawei Xu
Publicado em 2022-05-01

Immunogenomic intertumor heterogeneity across primary and metastatic sites in a patient with lung adenocarcinoma

Por Runzhe Chen, Jun Li, Junya Fujimoto, Lingzhi Hong, Xin Hu, Kelly Quek, Ming Tang, Akash Mitra, Carmen Behrens, Chi-Wan Chow, Peixin Jiang, Latasha D. Little, Curtis Gumbs, Xingzhi Song, Jianhua Zhang, Dongfeng Tan, John V. Heymach, Ignacio Wistuba, P. Andrew Futreal, Don L. Gibbons, Lauren A. Byers, Jianjun Zhang, Alexandre Reuben
Publicado em 2022-05-01

EIF4A3-induced circTOLLIP promotes the progression of hepatocellular carcinoma via the miR-516a-5p/PBX3/EMT pathway

Por Yachong Liu, Jia Song, Hongwei Zhang, Zhibin Liao, Furong Liu, Chen Su, Weijian Wang, Mengzhen Han, Lu Zhang, He Zhu, Zhanguo Zhang, Huifang Liang, Lei Zhang, Bixiang Zhang, Xiaoping Chen
Publicado em 2022-05-01

Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway

Por Zhi Li, Hai-Yan Yang, Xiao-Lan Zhang, Xu Zhang, Yu-Zhou Huang, Xin-Yuan Dai, Liang Shi, Guo-Ren Zhou, Ji-Fu Wei, Qiang Ding
Publicado em 2022-05-01

Elevated transcription and glycosylation of B3GNT5 promotes breast cancer aggressiveness

Por Zhaorui Miao, Qianhua Cao, Ruocen Liao, Xingyu Chen, Xiaoli Li, Longchang Bai, Chenglong Ma, Xinyue Deng, Zhijun Dai, Jun Li, Chenfang Dong
Publicado em 2022-05-01

Stanniocalcin 2 (STC2): a universal tumour biomarker and a potential therapeutical target

Por Shuo Qie, Nianli Sang
Publicado em 2022-05-01

Correction: Mechanical stress shapes the cancer cell response to neddylation inhibition

Por Frédérique Mittler, Patricia Obeïd, Vincent Haguet, Cédric Allier, Sophie Gerbaud, Anastasia V. Rulina, Xavier Gidrol, Maxim Y. Balakirev
Publicado em 2022-05-01

EIF4A3-regulated circ_0087429 can reverse EMT and inhibit the progression of cervical cancer via miR-5003-3p-dependent upregulation of OGN expression

Por Meiqin Yang, Haoran Hu, Sufang Wu, Jianyi Ding, Bo Yin, Baoyou Huang, Fang Li, Xiaoqing Guo, Lingfei Han
Publicado em 2022-05-01

Nanoengineering a metal–organic framework for osteosarcoma chemo-immunotherapy by modulating indoleamine-2,3-dioxygenase and myeloid-derived suppressor cells

Por Qingxin Fan, Jing Zuo, Hailong Tian, Canhua Huang, Edouard C. Nice, Zheng Shi, Qingquan Kong
Publicado em 2022-05-01

Sequence-dependent synergistic effect of aumolertinib-pemetrexed combined therapy on EGFR-mutant non-small-cell lung carcinoma with pre-clinical and clinical evidence

Por Luyao Ao, Shencun Fang, Kexin Zhang, Yang Gao, Jiawen Cui, Wenjing Jia, Yunlong Shan, Jingwei Zhang, Guangji Wang, Jiali Liu, Fang Zhou
Publicado em 2022-05-01

Interleukin-6 mediated inflammasome activation promotes oral squamous cell carcinoma progression via JAK2/STAT3/Sox4/NLRP3 signaling pathway

Por Li Xiao, Xue Li, Peilin Cao, Wei Fei, Hao Zhou, Na Tang, Yi Liu
Publicado em 2022-05-01

The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma

Por Silvia Lampis, Salvatore Raieli, Luca Montemurro, Damiano Bartolucci, Camilla Amadesi, Sonia Bortolotti, Silvia Angelucci, Anna Lisa Scardovi, Giammario Nieddu, Lucia Cerisoli, Francesca Paganelli, Sabrina Valente, Matthias Fischer, Alberto Maria Martelli, Gianandrea Pasquinelli, Andrea Pession, Patrizia Hrelia, Roberto Tonelli
Publicado em 2022-04-01