Cytotoxic and interactive effects of zearalenone, a-zearalenol and b-zearalenol and formation of metabolites in HepG2 cells

Zearalenone (ZEA) is a secondary metabolite of Fusarium fungi. ZEA is a non-steroidal estrogenic mycotoxin which is rapidly absorbed and metabolized to α-zearalenol (α-ZOL) and β-zearalenol (β-ZOL) in the liver; therefore mixtures of these mycotoxins may be simultaneously present in biological syste...

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Udgivet i:Revista de Toxicología
Main Authors: E Tatay, G Meca, G Font, MJ Ruiz
Format: Artigo
Sprog:Inglês
Udgivet: Asociación Española de Toxicología 2014
Fag:
Medicina
isobolas
zearalenone
HepG2 cells
metabolites
interactive effect
Online adgang:https://www.redalyc.org/articulo.oa?id=91932969015
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