Differential expression of human beta defensins in placenta and detection of allelic variants in the DEFB1 gene from HIV-1 positive mothers

Introduction. Low infection rates in neonates born to HIV-1-seropositive mothers highlight the existence of natural defense mechanisms in the maternal-fetal interface. Human beta defensins (HBDs) inhibit HIV-1 replication in vitro and their variants are associated with HIV-1 resistance/susceptibilit...

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Bibliografske podrobnosti
izdano v:Biomédica
Main Authors: Wbeimar Aguilar-Jiménez, Wildeman Zapata, María Teresa Rugeles
Format: Artigo
Jezik:Inglês
Izdano: Instituto Nacional de Salud 2011
Teme:
Medicina
HIV
innate
placenta
vertical
immunity
Online dostop:https://www.redalyc.org/articulo.oa?id=84322444007
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