Variation in the number of EPIYA-C repeats in CagA protein from Colombian Helicobacter pylori strains and its ability middle to induce hummingbird phenotype in gastric epithelial cells

Introduction. Studies using Western Helicobacter pylori strains have shown that a risk factor for gastric cancer is the number of EPIYA-C motifs in the cytotoxin-associated A protein. CagA is delivered into epithelial cells, where it becomes tyrosine phosphorylated in their EPIYA repeats and induces...

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Detalhes bibliográficos
Publicado no:Biomédica
Main Authors: Andrés Javier Quiroga, Antonio Huertas, Alba Lucía Cómbita, María Mercedes Bravo
Formato: Artigo
Idioma:Inglês
Publicado em: Instituto Nacional de Salud 2010
Assuntos:
Medicina
genetic
gastritis
polymorphism
duodenal ulcer
stomach neoplasm
Acesso em linha:https://www.redalyc.org/articulo.oa?id=84316246012
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