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Significance of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer patients receiving Bevacizumab: a single institution experience

KRAS mutation is an important predictive and prognostic factor for patients receiving anti-EGFR therapy. An expanded KRAS, NRAS, BRAF, PIK3CA mutation analysis provides additional prognostic information, but its role in predicting bevacizumab efficacy is unclear. T he aim of our study was to evaluat...

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Pubblicato in:Acta medica Lituanica
Autori principali: Edita Baltruškevičienė, Ugnius Mickys, Tadas Žvirblis, Rokas Stulpinas, Teresė Pipirienė Želvienė, Eduardas Aleknavičius
Natura: Artigo
Lingua:Francês
Pubblicazione: Vilniaus Universitetas 2016
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Accesso online:https://www.redalyc.org/articulo.oa?id=694073987006
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