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Development and validation of a method for the determination of valproic acid in pharmaceutical formulations by high performance liquid chromatography with diode array detection (HPLC-DAD)

Valproic acid (VA) is used as an anticonvulsant and is used in the treatment of bipolar disorder and depression. The offi cial analytical method for this drug in the compendia is gas chromatography, which is unavailable in many quality control laboratories. Here, we report a validated alternative me...

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Publié dans:Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia
Auteurs principaux: Paulo Ricardo de Souza e Souza, Juliana Machado de Carvalho, André Luis Mazzei Albert, Josino Costa Moreira, Katia Christina Leandro
Format: Artigo
Langue:Inglês
Publié: Fundação Oswaldo Cruz 2013
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Accès en ligne:https://www.redalyc.org/articulo.oa?id=570561855008
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