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Preparation of (+)- and (−)- B-phenyl- and B-(4-chlorophenyl)-y-butyrolactones: Key Intermediates in the Synthesis of B-phenyl-GABA and Baclofen.
Thepreparationofβ-phenyl-andβ-(4-chlorophenyl)-γ-bu-tyrolactones( ± )-3and( ± )-4andtheirresolutiontothecorrespond-ing(+)-(S)-3, (−)-(R)-3and(+)-(S)-4, (−)-(R)-4throughformation,flashcolumnchromatographyseparationandsubsequenthydrolysisofdiastereoisomeric4-hydroxybutyramides(2’R,3S)-5,(2’R,3R)-5,(2’...
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| Publicado no: | Journal of the Mexican Chemical Society |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Sociedad Química de México
2015
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| Assuntos: | |
| Acesso em linha: | https://www.redalyc.org/articulo.oa?id=47539242003 |
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