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Side-chain opening of steroidal sapogenins to form 22-oxocholestanic skeletons. An approach to analogues of the aglycone of the potent anticancer agent OSW-1

The side-chain opening of 25R and 25S steroidal sapogenins to form 22-oxocholestanic skeletons is described. The transformation was produced under mild conditions providing high yields (70-87%), in a one pot procedure (some acetylated starting material is recovered). This methodology yields 17-deoxy...

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Bibliografski detalji
Izdano u:Journal of the Mexican Chemical Society
Glavni autori: María A. Fernández-Herrera, Jesús Sandoval-Ramírez, Socorro Meza-Reyes, Sara Montiel-Smith
Format: Artigo
Jezik:Inglês
Izdano: Sociedad Química de México 2009
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Online pristup:https://www.redalyc.org/articulo.oa?id=47512154007
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