Relevance of the ancestry for the variability of the Drug-Metabolizing Enzymes CYP2C9, CYP2C19 and CYP2D6 polymorphisms in a multiethnic Costa Rican population

CYP2C9, CYP2C19 and CYP2D6 metabolize around 40 % of drugs and their genes vary across populations. The Costa Rican population has a trihybrid ancestry and its key geographic location turns it into a suitable scenario to evaluate interethnic differences across populations. This stud...

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Detalhes bibliográficos

Publicado no:	Revista de Biología Tropical
Principais autores:	Carolina Céspedes-Garro, Fernanda Rodrigues-Soares, Gerardo Jiménez-Arce, María-Eugenia G. Naranjo, Eduardo Tarazona-Santos, Humberto Fariñas, Ramiro Barrantes, Adrián Llerena, CEIBA.FP Consortium of the Ibero-American Network of Pharmacogenetics & Pharmacogenomics RIBEF
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Universidad de Costa Rica 2016
Assuntos:	Biología
Acesso em linha:	https://www.redalyc.org/articulo.oa?id=44946472012 https://www.redalyc.org/journal/449/44946472012/ https://www.redalyc.org/journal/449/44946472012/html/ https://www.redalyc.org/journal/449/44946472012/44946472012.epub https://www.redalyc.org/journal/449/44946472012/movil
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