Short-term low-protein diet during pregnancy alters islet area and protein content of phosphatidylinositol 3-kinase pathway in rats

The phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways mediate β cell growth, proliferation, survival and death. We investigated whether protein restriction during pregnancy alters islet morphometry or the expression and phosphorylation of several proteins involv...

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Vydáno v:Anais da Academia Brasileira de Ciências
Hlavní autoři: CRISTIANA S.B. SALVATIERRA, SÍLVIA R.L. REIS, ANA F.M. PESSOA, LETÍCIA M.I. DE SOUZA, LUIZ F. STOPPIGLIA, ROBERTO V. VELOSO, MARISE A.B. REIS, EVERARDO M. CARNEIRO, ANTONIO C. BOSCHERO, EDSON M. COLODEL, VANESSA C. ARANTES, MÁRCIA Q. LATORRACA
Médium: Artigo
Jazyk:Inglês
Vydáno: Academia Brasileira de Ciências 2015
Témata:
Multidisciplinaria (Ciencias Naturales y Exactas)
rats
pregnancy
PI3K pathway
pancreatic islets
MAP kinase pathway
On-line přístup:https://www.redalyc.org/articulo.oa?id=32739721037
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