Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity

Anti-tuberculosis drug-induced hepatitis (ATD- induced hepatitis) has been linked to polymorphisms in genes encoding drug metabolizing enzymes. N-acetyltransferase 2 (NAT2), cytochrome P450 2E1 (CYP2E1) and glutathione S-transferase (loci GSTM1 and GSTT1) are involved in the metabolism of isoniazid,...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Anais da Academia Brasileira de Ciências
Hlavní autoři: TAIS C. BRITO, LIA G. POSSUELO, ANDREIA R.M. VALIM, PÂMELA F. TODENDI, ANDREZZA W. RIBEIRO, TATIANA S. GREGIANINI, CARLA A. JARCZEWSKI, MARA H. HUTZ, MARIA LUCIA R. ROSSETTI, ARNALDO ZAHA
Médium: Artigo
Jazyk:Inglês
Vydáno: Academia Brasileira de Ciências 2014
Témata:
Multidisciplinaria (Ciencias Naturales y Exactas)
isoniazid
tuberculosis
polymorphisms
Hepatotoxicity
On-line přístup:https://www.redalyc.org/articulo.oa?id=32731288028
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky