Limited replication of yellow fever 17DD and 17D-Dengue recombinant viruses in rhesus monkeys

For the development of safe live attenuated flavivirus vaccines one of the main properties to be established is viral replication. We have used real-time reverse transcriptase-polymerase chain reaction and virus titration by plaque assay to determine the replication of yellow fever 17DD virus (YFV 1...

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Bibliographische Detailangaben
Veröffentlicht in:Anais da Academia Brasileira de Ciências
Hauptverfasser: Gisela F. Trindade, Renato S. Marchevsky, Ana M.B. de Fillipis, Rita M.R. Nogueira, Myrna C. Bonaldo, Pedro C. Acero, Elena Caride, Marcos S. Freire, Ricardo Galler
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academia Brasileira de Ciências 2008
Schlagworte:
Multidisciplinaria (Ciencias Naturales y Exactas)
PCR
real
dengue
vaccine
time RT
Online Zugang:https://www.redalyc.org/articulo.oa?id=32713458009
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