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De-N-acetylated sialic acid is immunogenic and elicits antibodies that are protective against Neisseria meningitidis

Recently, we showed that monoclonal antibodies (mAbs) that are reactive with derivatives of polysialic acid containing de-N-acetylated neuraminic acid (Neu) residues are protective against N. meningitidis group B strains (Moe et al. 2005, Infect Immun 73:2123; Flitter et al., in preparation). In add...

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Bibliografische Detailangaben
Veröffentlicht in:VacciMonitor
Hauptverfasser: Gregory R. Moe, Becca A. Flitter, Jessica Y. Ing, Tamara S. Bhandari, Hardeep Kaur
Format: Artigo
Sprache:Inglês
Veröffentlicht: Instituto Finlay 2009
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Online-Zugang:https://www.redalyc.org/articulo.oa?id=203414610004
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