The Methylosome, a 20S Complex Containing JBP1 and pICln, Produces Dimethylarginine-Modified Sm Proteins

snRNPs, integral components of the pre-mRNA splicing machinery, consist of seven Sm proteins which assemble in the cytoplasm as a ring structure on the snRNAs U1, U2, U4, and U5. The survival motor neuron (SMN) protein, the spinal muscular atrophy disease gene product, is crucial for snRNP core part...

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Bibliografiska uppgifter
Huvudupphovsmän: Friesen, Westley J., Paushkin, Sergey, Wyce, Anastasia, Massenet, Severine, Pesiridis, G. Scott, Van Duyne, Gregory, Rappsilber, Juri, Mann, Matthias, Dreyfuss, Gideon
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2001
Ämnen:
Gene Expression
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC99994/
https://ncbi.nlm.nih.gov/pubmed/11713266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8289-8300.2001
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