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8p12 Stem Cell Myeloproliferative Disorder: the FOP-Fibroblast Growth Factor Receptor 1 Fusion Protein of the t(6;8) Translocation Induces Cell Survival Mediated by Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase/Akt/mTOR Pathways

The FOP-fibroblast growth factor receptor 1 (FGFR1) fusion protein is expressed as a consequence of a t(6;8) (q27;p12) translocation associated with a stem cell myeloproliferative disorder with lymphoma, myeloid hyperplasia and eosinophilia. In the present report, we show that the fusion of the leuc...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Guasch, Géraldine, Ollendorff, Vincent, Borg, Jean-Paul, Birnbaum, Daniel, Pébusque, Marie-Josèphe
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99978/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689702/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.23.8129-8142.2001
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