Individual Somatic H1 Subtypes Are Dispensable for Mouse Development Even in Mice Lacking the H1(0) Replacement Subtype

H1 linker histones are involved in facilitating the folding of chromatin into a 30-nm fiber. Mice contain eight H1 subtypes that differ in amino acid sequence and expression during development. Previous work showed that mice lacking H1(0), the most divergent subtype, develop normally. Examination of...

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Autori principali: Fan, Yuhong, Sirotkin, Allen, Russell, Robert G., Ayala, Julianna, Skoultchi, Arthur I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC99962/
https://ncbi.nlm.nih.gov/pubmed/11689686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.23.7933-7943.2001
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