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p300 Acts as a Transcriptional Coactivator for Mammalian Notch-1

Notch-1 belongs to a family of transmembrane receptor proteins that direct the decisions as to various cell fates. After ligand binding, a proteolytic cleavage step occurs and the intracellular part of Notch-1, Notch-1-IC, translocates into the nucleus, where it targets the DNA binding protein RBP-J...

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Published in:Mol Cell Biol
Main Authors: Oswald, Franz, Täuber, Birgitt, Dobner, Thomas, Bourteele, Soizic, Kostezka, Ulrike, Adler, Guido, Liptay, Susanne, Schmid, Roland M.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2001
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11604511/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.22.7761-7774.2001
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