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Downregulation of the Ras–Mitogen-Activated Protein Kinase Pathway by the EphB2 Receptor Tyrosine Kinase Is Required for Ephrin-Induced Neurite Retraction

Activation of the EphB2 receptor tyrosine kinase by clustered ephrin-B1 induces growth cone collapse and neurite retraction in differentiated NG108 neuronal cells. We have investigated the cytoplasmic signaling events associated with EphB2-induced cytoskeletal reorganization in these neuronal cells....

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Main Authors: Elowe, Sabine, Holland, Sacha J., Kulkarni, Sarang, Pawson, Tony
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC99915/
https://ncbi.nlm.nih.gov/pubmed/11585923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7429-7441.2001
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