Targeting of the Yeast Ty5 Retrotransposon to Silent Chromatin Is Mediated by Interactions between Integrase and Sir4p

The Ty5 retrotransposons of Saccharomyces cerevisiae integrate preferentially into regions of silent chromatin at the telomeres and silent mating loci (HMR and HML). We define a Ty5-encoded targeting domain that spans 6 amino acid residues near the C terminus of integrase (LXSSXP). The targeting dom...

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Detalhes bibliográficos
Main Authors: Xie, Weiwu, Gai, Xiaowu, Zhu, Yunxia, Zappulla, David C., Sternglanz, Rolf, Voytas, Daniel F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99806/
https://ncbi.nlm.nih.gov/pubmed/11533248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.19.6606-6614.2001
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