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Targeting of the Yeast Ty5 Retrotransposon to Silent Chromatin Is Mediated by Interactions between Integrase and Sir4p

The Ty5 retrotransposons of Saccharomyces cerevisiae integrate preferentially into regions of silent chromatin at the telomeres and silent mating loci (HMR and HML). We define a Ty5-encoded targeting domain that spans 6 amino acid residues near the C terminus of integrase (LXSSXP). The targeting dom...

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Autori principali: Xie, Weiwu, Gai, Xiaowu, Zhu, Yunxia, Zappulla, David C., Sternglanz, Rolf, Voytas, Daniel F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC99806/
https://ncbi.nlm.nih.gov/pubmed/11533248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.19.6606-6614.2001
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