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Human MCF10A Mammary Epithelial Cells Undergo Apoptosis following Actin Depolymerization That Is Independent of Attachment and Rescued by Bcl-2

Many tumor cells are impaired in adhesion-regulated apoptosis, which contributes to their metastatic potential. However, suppression of this apoptotic pathway in untransformed cells is not mediated only by adhesion to the extracellular matrix but also through the resulting ability to spread and adop...

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Bibliografiske detaljer
Main Authors: Martin, Stuart S., Leder, Philip
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC99799/
https://ncbi.nlm.nih.gov/pubmed/11533241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.19.6529-6536.2001
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