Upc2p and Ecm22p, Dual Regulators of Sterol Biosynthesis in Saccharomyces cerevisiae

Sterol levels affect the expression of many genes in yeast and humans. We found that the paralogous transcription factors Upc2p and Ecm22p of yeast were sterol regulatory element (SRE) binding proteins (SREBPs) responsible for regulating transcription of the sterol biosynthetic genes ERG2 and ERG3....

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Bibliographic Details
Main Authors: Vik, Åshild, Rine, Jasper
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC99787/
https://ncbi.nlm.nih.gov/pubmed/11533229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.19.6395-6405.2001
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