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Hepatocyte Nuclear Factor 4α (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis

The numerous functions of the liver are controlled primarily at the transcriptional level by the concerted actions of a limited number of hepatocyte-enriched transcription factors (hepatocyte nuclear factor 1α [HNF1α], -1β, -3α, -3β, -3γ, -4α, and -6 and members of the c/ebp family). Of these, only...

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Main Authors: Hayhurst, Graham P., Lee, Ying-Hue, Lambert, Gilles, Ward, Jerrold M., Gonzalez, Frank J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC99591/
https://ncbi.nlm.nih.gov/pubmed/11158324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.4.1393-1403.2001
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