The PEA3 Subfamily of Ets Transcription Factors Synergizes with β-Catenin–LEF-1 To Activate Matrilysin Transcription in Intestinal Tumors

The matrix metalloproteinase matrilysin (MMP-7) is expressed in the tumor cells of a majority of mouse intestinal and human colonic adenomas. We showed previously that matrilysin is a target gene of β-catenin–Tcf, the transcription factor complex whose activity is thought to play a crucial role in t...

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Autori principali: Crawford, Howard C., Fingleton, Barbara, Gustavson, Mark D., Kurpios, Natasza, Wagenaar, Rebecca A., Hassell, John A., Matrisian, Lynn M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC99589/
https://ncbi.nlm.nih.gov/pubmed/11158322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.4.1370-1383.2001
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