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Specificity and Topology of the Escherichia coli Xanthosine Permease, a Representative of the NHS Subfamily of the Major Facilitator Superfamily
The specificity of XapB permease was compared with that of the known nucleoside transporters NupG and NupC. XapB-mediated xanthosine uptake is abolished by 2,4-dinitrophenol and exhibits saturation kinetics with an apparent K(m) of 136 μM. A 12-transmembrane-segment model was confirmed by translatio...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC99545/ https://ncbi.nlm.nih.gov/pubmed/11466294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.16.4900-4904.2001 |
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