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Specificity and Topology of the Escherichia coli Xanthosine Permease, a Representative of the NHS Subfamily of the Major Facilitator Superfamily

The specificity of XapB permease was compared with that of the known nucleoside transporters NupG and NupC. XapB-mediated xanthosine uptake is abolished by 2,4-dinitrophenol and exhibits saturation kinetics with an apparent K(m) of 136 μM. A 12-transmembrane-segment model was confirmed by translatio...

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Autors principals: Nørholm, Morten H. H., Dandanell, Gert
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC99545/
https://ncbi.nlm.nih.gov/pubmed/11466294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.16.4900-4904.2001
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