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Blockade of Caspases Inhibits Amebic Liver Abscess Formation in a Mouse Model of Disease

We looked at the effect of inhibiting caspases on amebic liver abscess in the mouse model of infection. A dose of the pan-caspase inhibitor benzyloxycarbonyl-V-A-D-O-methyl fluoromethyl ketone (Z-VAD-FMK; R & D Systems) given to SCID mice 2 h prior to direct hepatic inoculation with Entamoeba hi...

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Detalhes bibliográficos
Main Authors: Yan, Le, Stanley, Samuel L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98890/
https://ncbi.nlm.nih.gov/pubmed/11705976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7911-7914.2001
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