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Role of Complement in Mycobacterium avium Pathogenesis: In Vivo and In Vitro Analyses of the Host Response to Infection in the Absence of Complement Component C3

We investigated the importance of the host complement system in the pathogenesis of disease mediated by the intramacrophage pathogen Mycobacterium avium. Mycobacteria opsonized with complement are efficiently ingested by macrophages through various complement receptors. Furthermore, unlike other bac...

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Détails bibliographiques
Auteurs principaux: Bohlson, Suzanne S., Strasser, Jennifer A., Bower, Jacquelyn J., Schorey, Jeffrey S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC98868/
https://ncbi.nlm.nih.gov/pubmed/11705954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7729-7735.2001
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