Role of RgpA, RgpB, and Kgp Proteinases in Virulence of Porphyromonas gingivalis W50 in a Murine Lesion Model

Extracellular Arg-x- and Lys-x-specific cysteine proteinases are considered important virulence factors and pathogenic markers for Porphyromonas gingivalis, a bacterium implicated as a major etiological agent of chronic periodontitis. Three genes. rgpA, rgpB, and kgp, encode an Arg-x-specific protei...

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Autors principals: O'Brien-Simpson, Neil M., Paolini, Rita A., Hoffmann, Brigitte, Slakeski, Nada, Dashper, Stuart G., Reynolds, Eric C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Molecular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98843/
https://ncbi.nlm.nih.gov/pubmed/11705929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7527-7534.2001
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