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Pathoadaptive Mutations That Enhance Virulence: Genetic Organization of the cadA Regions of Shigella spp.

Pathoadaptive mutations improve the fitness of pathogenic species by modification of traits that interfere with factors (virulence and ancestral) required for survival in host tissues. A demonstrated pathoadaptive mutation is the loss of lysine decarboxylase (LDC) expression in Shigella species that...

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Detalhes bibliográficos
Main Authors: Day, William A., Fernández, Reinaldo E., Maurelli, Anthony T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98836/
https://ncbi.nlm.nih.gov/pubmed/11705922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7471-7480.2001
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