High Extracellular Levels of Mycobacterium tuberculosis Glutamine Synthetase and Superoxide Dismutase in Actively Growing Cultures Are Due to High Expression and Extracellular Stability Rather than to a Protein-Specific Export Mechanism

Glutamine synthetase (GS) and superoxide dismutase (SOD), large multimeric enzymes that are thought to play important roles in the pathogenicity of Mycobacterium tuberculosis, are among the bacterium's major culture filtrate proteins in actively growing cultures. Although these proteins lack a...

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Bibliographische Detailangaben
Hauptverfasser: Tullius, Michael V., Harth, Günter, Horwitz, Marcus A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98770/
https://ncbi.nlm.nih.gov/pubmed/11553579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6348-6363.2001
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