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Interdependency of Interleukin-10 and Interleukin-12 in Regulation of T-Cell Differentiation and Effector Function of Monocytes in Response to Stimulation with Cryptococcus neoformans

We previously demonstrated that the principal component of capsular material of Cryptococcus neoformans, glucuronoxylomannan (GXM), induces interleukin-10 (IL-10) secretion from human monocytes. Here we report that encapsulation of the yeast with GXM is able to down-regulate interleukin-12 (IL-12) p...

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Detalles Bibliográficos
Main Authors: Retini, Cinzia, Kozel, Thomas R., Pietrella, Donatella, Monari, Claudia, Bistoni, Francesco, Vecchiarelli, Anna
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC98735/
https://ncbi.nlm.nih.gov/pubmed/11553544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6064-6073.2001
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